HTR1B protein (Gorilla gorilla) - STRING interaction network

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HTR1B

5-hydroxytryptamine receptor 1B; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopami [...] (390 aa)

Predicted Functional Partners:

ENSGGOP00000038515

0.939

GNB1

0.935

GNG2

0.934

GNB4

0.877

GNG7

0.832

GNG4

0.812

GNAI1

0.811

GNAI3

0.811

GNB3

0.800

GNB2

0.796

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSGGOP00000038515	GNAI1	ENSGGOP00000038515	ENSGGOP00000007886	G protein subunit alpha o1.	G protein subunit alpha i1.	0.981
ENSGGOP00000038515	GNAI3	ENSGGOP00000038515	ENSGGOP00000025924	G protein subunit alpha o1.	G protein subunit alpha i3.	0.979
ENSGGOP00000038515	GNB1	ENSGGOP00000038515	ENSGGOP00000035487	G protein subunit alpha o1.	G protein subunit beta 1.	0.989
ENSGGOP00000038515	GNB2	ENSGGOP00000038515	ENSGGOP00000040379	G protein subunit alpha o1.	G protein subunit beta 2.	0.982
ENSGGOP00000038515	GNB3	ENSGGOP00000038515	ENSGGOP00000002568	G protein subunit alpha o1.	G protein subunit beta 3.	0.979
ENSGGOP00000038515	GNB4	ENSGGOP00000038515	ENSGGOP00000025314	G protein subunit alpha o1.	G protein subunit beta 4.	0.989
ENSGGOP00000038515	GNG2	ENSGGOP00000038515	ENSGGOP00000029199	G protein subunit alpha o1.	G protein gamma domain-containing protein.	0.980
ENSGGOP00000038515	GNG4	ENSGGOP00000038515	ENSGGOP00000007723	G protein subunit alpha o1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.974
ENSGGOP00000038515	GNG7	ENSGGOP00000038515	ENSGGOP00000045049	G protein subunit alpha o1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.966
ENSGGOP00000038515	HTR1B	ENSGGOP00000038515	ENSGGOP00000019686	G protein subunit alpha o1.	5-hydroxytryptamine receptor 1B; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopami [...]	0.939
GNAI1	ENSGGOP00000038515	ENSGGOP00000007886	ENSGGOP00000038515	G protein subunit alpha i1.	G protein subunit alpha o1.	0.981
GNAI1	GNAI3	ENSGGOP00000007886	ENSGGOP00000025924	G protein subunit alpha i1.	G protein subunit alpha i3.	0.999
GNAI1	GNB1	ENSGGOP00000007886	ENSGGOP00000035487	G protein subunit alpha i1.	G protein subunit beta 1.	0.997
GNAI1	GNB2	ENSGGOP00000007886	ENSGGOP00000040379	G protein subunit alpha i1.	G protein subunit beta 2.	0.987
GNAI1	GNB3	ENSGGOP00000007886	ENSGGOP00000002568	G protein subunit alpha i1.	G protein subunit beta 3.	0.976
GNAI1	GNB4	ENSGGOP00000007886	ENSGGOP00000025314	G protein subunit alpha i1.	G protein subunit beta 4.	0.995
GNAI1	GNG2	ENSGGOP00000007886	ENSGGOP00000029199	G protein subunit alpha i1.	G protein gamma domain-containing protein.	0.984
GNAI1	GNG4	ENSGGOP00000007886	ENSGGOP00000007723	G protein subunit alpha i1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.994
GNAI1	GNG7	ENSGGOP00000007886	ENSGGOP00000045049	G protein subunit alpha i1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.994
GNAI1	HTR1B	ENSGGOP00000007886	ENSGGOP00000019686	G protein subunit alpha i1.	5-hydroxytryptamine receptor 1B; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopami [...]	0.811

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