ACLY protein (Gorilla gorilla) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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co-expression

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gene neighborhood

gene co-occurrence

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Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACACA	ACLY	ENSGGOP00000016675	ENSGGOP00000020058	Acetyl-CoA carboxylase alpha.	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	0.945
ACACA	CS	ENSGGOP00000016675	ENSGGOP00000022736	Acetyl-CoA carboxylase alpha.	Citrate synthase; Belongs to the citrate synthase family.	0.836
ACACA	DLAT	ENSGGOP00000016675	ENSGGOP00000002482	Acetyl-CoA carboxylase alpha.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.919
ACACA	FASN	ENSGGOP00000016675	ENSGGOP00000011384	Acetyl-CoA carboxylase alpha.	Fatty acid synthase.	0.982
ACACA	PC	ENSGGOP00000016675	ENSGGOP00000014135	Acetyl-CoA carboxylase alpha.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.640
ACLY	ACACA	ENSGGOP00000020058	ENSGGOP00000016675	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Acetyl-CoA carboxylase alpha.	0.945
ACLY	ACO1	ENSGGOP00000020058	ENSGGOP00000015930	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Aconitase 1; Belongs to the aconitase/IPM isomerase family.	0.954
ACLY	ACO2	ENSGGOP00000020058	ENSGGOP00000001092	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.955
ACLY	CS	ENSGGOP00000020058	ENSGGOP00000022736	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Citrate synthase; Belongs to the citrate synthase family.	0.986
ACLY	DLAT	ENSGGOP00000020058	ENSGGOP00000002482	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.977
ACLY	FASN	ENSGGOP00000020058	ENSGGOP00000011384	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Fatty acid synthase.	0.991
ACLY	MDH1	ENSGGOP00000020058	ENSGGOP00000039797	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Malate dehydrogenase.	0.958
ACLY	MDH2	ENSGGOP00000020058	ENSGGOP00000011503	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Malate dehydrogenase.	0.958
ACLY	PC	ENSGGOP00000020058	ENSGGOP00000014135	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.946
ACLY	PCK1	ENSGGOP00000020058	ENSGGOP00000010716	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Phosphoenolpyruvate carboxykinase 1.	0.925
ACO1	ACLY	ENSGGOP00000015930	ENSGGOP00000020058	Aconitase 1; Belongs to the aconitase/IPM isomerase family.	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	0.954
ACO1	ACO2	ENSGGOP00000015930	ENSGGOP00000001092	Aconitase 1; Belongs to the aconitase/IPM isomerase family.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.928
ACO1	CS	ENSGGOP00000015930	ENSGGOP00000022736	Aconitase 1; Belongs to the aconitase/IPM isomerase family.	Citrate synthase; Belongs to the citrate synthase family.	0.992
ACO1	DLAT	ENSGGOP00000015930	ENSGGOP00000002482	Aconitase 1; Belongs to the aconitase/IPM isomerase family.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.401
ACO1	MDH1	ENSGGOP00000015930	ENSGGOP00000039797	Aconitase 1; Belongs to the aconitase/IPM isomerase family.	Malate dehydrogenase.	0.558