FOXA2 protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EP300	ESR1	ENSGGOP00000008032	ENSGGOP00000009454	E1A binding protein p300.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.982
EP300	FOXA2	ENSGGOP00000008032	ENSGGOP00000020817	E1A binding protein p300.	Forkhead box A2.	0.892
EP300	G3R5D7_GORGO	ENSGGOP00000008032	ENSGGOP00000010510	E1A binding protein p300.	Uncharacterized protein.	0.766
EP300	GATA2	ENSGGOP00000008032	ENSGGOP00000006023	E1A binding protein p300.	GATA binding protein 2.	0.762
EP300	GATA3	ENSGGOP00000008032	ENSGGOP00000006027	E1A binding protein p300.	GATA binding protein 3.	0.925
EP300	NRIP1	ENSGGOP00000008032	ENSGGOP00000050716	E1A binding protein p300.	Nuclear receptor interacting protein 1.	0.858
ESR1	EP300	ENSGGOP00000009454	ENSGGOP00000008032	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	E1A binding protein p300.	0.982
ESR1	FOXA2	ENSGGOP00000009454	ENSGGOP00000020817	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Forkhead box A2.	0.891
ESR1	G3R5D7_GORGO	ENSGGOP00000009454	ENSGGOP00000010510	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Uncharacterized protein.	0.412
ESR1	GATA2	ENSGGOP00000009454	ENSGGOP00000006023	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	GATA binding protein 2.	0.685
ESR1	GATA3	ENSGGOP00000009454	ENSGGOP00000006027	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	GATA binding protein 3.	0.924
ESR1	NRIP1	ENSGGOP00000009454	ENSGGOP00000050716	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor interacting protein 1.	0.963
ESR1	RPS6KB1	ENSGGOP00000009454	ENSGGOP00000019074	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Protein kinase domain-containing protein.	0.944
ESR1	RPS6KB2	ENSGGOP00000009454	ENSGGOP00000009763	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.926
FOXA2	EP300	ENSGGOP00000020817	ENSGGOP00000008032	Forkhead box A2.	E1A binding protein p300.	0.892
FOXA2	ESR1	ENSGGOP00000020817	ENSGGOP00000009454	Forkhead box A2.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.891
FOXA2	G3R5D7_GORGO	ENSGGOP00000020817	ENSGGOP00000010510	Forkhead box A2.	Uncharacterized protein.	0.950
FOXA2	GATA2	ENSGGOP00000020817	ENSGGOP00000006023	Forkhead box A2.	GATA binding protein 2.	0.878
FOXA2	GATA3	ENSGGOP00000020817	ENSGGOP00000006027	Forkhead box A2.	GATA binding protein 3.	0.966
FOXA2	MIXL1	ENSGGOP00000020817	ENSGGOP00000002089	Forkhead box A2.	Mix paired-like homeobox.	0.889