GFI1 protein (Gorilla gorilla) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

GFI1

Growth factor independent 1 transcriptional repressor. (422 aa)

Predicted Functional Partners:

KDM1A

0.823

CEBPA

0.776

GATA2

0.754

GATA1

0.738

HDAC1

0.730

RCOR1

0.713

EHMT2

0.707

HDAC2

0.695

ATXN1

0.677

POU4F3

0.673

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATXN1	GFI1	ENSGGOP00000004089	ENSGGOP00000005209	Ataxin 1.	Growth factor independent 1 transcriptional repressor.	0.677
CEBPA	GATA1	ENSGGOP00000038288	ENSGGOP00000018626	BZIP domain-containing protein.	GATA binding protein 1.	0.700
CEBPA	GATA2	ENSGGOP00000038288	ENSGGOP00000006023	BZIP domain-containing protein.	GATA binding protein 2.	0.761
CEBPA	GFI1	ENSGGOP00000038288	ENSGGOP00000005209	BZIP domain-containing protein.	Growth factor independent 1 transcriptional repressor.	0.776
CEBPA	HDAC1	ENSGGOP00000038288	ENSGGOP00000011454	BZIP domain-containing protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.805
CEBPA	HDAC2	ENSGGOP00000038288	ENSGGOP00000005320	BZIP domain-containing protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.484
EHMT2	GFI1	ENSGGOP00000049968	ENSGGOP00000005209	Euchromatic histone lysine methyltransferase 2.	Growth factor independent 1 transcriptional repressor.	0.707
EHMT2	HDAC1	ENSGGOP00000049968	ENSGGOP00000011454	Euchromatic histone lysine methyltransferase 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.958
EHMT2	HDAC2	ENSGGOP00000049968	ENSGGOP00000005320	Euchromatic histone lysine methyltransferase 2.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.866
EHMT2	KDM1A	ENSGGOP00000049968	ENSGGOP00000003605	Euchromatic histone lysine methyltransferase 2.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.873
EHMT2	RCOR1	ENSGGOP00000049968	ENSGGOP00000005215	Euchromatic histone lysine methyltransferase 2.	REST corepressor 1.	0.802
GATA1	CEBPA	ENSGGOP00000018626	ENSGGOP00000038288	GATA binding protein 1.	BZIP domain-containing protein.	0.700
GATA1	GATA2	ENSGGOP00000018626	ENSGGOP00000006023	GATA binding protein 1.	GATA binding protein 2.	0.824
GATA1	GFI1	ENSGGOP00000018626	ENSGGOP00000005209	GATA binding protein 1.	Growth factor independent 1 transcriptional repressor.	0.738
GATA1	HDAC1	ENSGGOP00000018626	ENSGGOP00000011454	GATA binding protein 1.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.692
GATA1	HDAC2	ENSGGOP00000018626	ENSGGOP00000005320	GATA binding protein 1.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.599
GATA2	CEBPA	ENSGGOP00000006023	ENSGGOP00000038288	GATA binding protein 2.	BZIP domain-containing protein.	0.761
GATA2	GATA1	ENSGGOP00000006023	ENSGGOP00000018626	GATA binding protein 2.	GATA binding protein 1.	0.824
GATA2	GFI1	ENSGGOP00000006023	ENSGGOP00000005209	GATA binding protein 2.	Growth factor independent 1 transcriptional repressor.	0.754
GATA2	HDAC1	ENSGGOP00000006023	ENSGGOP00000011454	GATA binding protein 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.489