| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| G3QHL6_GORGO | IKBKG | ENSGGOP00000001846 | ENSGGOP00000004800 | Interleukin 1 receptor associated kinase 2. | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | 0.748 |
| G3QHL6_GORGO | IRAK1 | ENSGGOP00000001846 | ENSGGOP00000018313 | Interleukin 1 receptor associated kinase 2. | Interleukin 1 receptor associated kinase 1. | 0.930 |
| G3QHL6_GORGO | MAP3K7 | ENSGGOP00000001846 | ENSGGOP00000020634 | Interleukin 1 receptor associated kinase 2. | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.685 |
| G3QHL6_GORGO | MYD88 | ENSGGOP00000001846 | ENSGGOP00000003761 | Interleukin 1 receptor associated kinase 2. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | 0.997 |
| G3QHL6_GORGO | SQSTM1 | ENSGGOP00000001846 | ENSGGOP00000020182 | Interleukin 1 receptor associated kinase 2. | Sequestosome 1. | 0.593 |
| G3QHL6_GORGO | TAB1 | ENSGGOP00000001846 | ENSGGOP00000007837 | Interleukin 1 receptor associated kinase 2. | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. | 0.814 |
| G3QHL6_GORGO | TAB2 | ENSGGOP00000001846 | ENSGGOP00000016323 | Interleukin 1 receptor associated kinase 2. | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. | 0.937 |
| G3QHL6_GORGO | TRAF6 | ENSGGOP00000001846 | ENSGGOP00000005734 | Interleukin 1 receptor associated kinase 2. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.998 |
| G3QHL6_GORGO | UBE2N | ENSGGOP00000001846 | ENSGGOP00000033905 | Interleukin 1 receptor associated kinase 2. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.713 |
| G3R3U7_GORGO | IKBKG | ENSGGOP00000009929 | ENSGGOP00000004800 | Mitochondrial antiviral signaling protein. | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | 0.890 |
| G3R3U7_GORGO | IRAK1 | ENSGGOP00000009929 | ENSGGOP00000018313 | Mitochondrial antiviral signaling protein. | Interleukin 1 receptor associated kinase 1. | 0.540 |
| G3R3U7_GORGO | MYD88 | ENSGGOP00000009929 | ENSGGOP00000003761 | Mitochondrial antiviral signaling protein. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | 0.698 |
| G3R3U7_GORGO | SQSTM1 | ENSGGOP00000009929 | ENSGGOP00000020182 | Mitochondrial antiviral signaling protein. | Sequestosome 1. | 0.564 |
| G3R3U7_GORGO | TRAF6 | ENSGGOP00000009929 | ENSGGOP00000005734 | Mitochondrial antiviral signaling protein. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.999 |
| IKBKG | G3QHL6_GORGO | ENSGGOP00000004800 | ENSGGOP00000001846 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Interleukin 1 receptor associated kinase 2. | 0.748 |
| IKBKG | G3R3U7_GORGO | ENSGGOP00000004800 | ENSGGOP00000009929 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Mitochondrial antiviral signaling protein. | 0.890 |
| IKBKG | IRAK1 | ENSGGOP00000004800 | ENSGGOP00000018313 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Interleukin 1 receptor associated kinase 1. | 0.996 |
| IKBKG | MAP3K7 | ENSGGOP00000004800 | ENSGGOP00000020634 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.999 |
| IKBKG | MYD88 | ENSGGOP00000004800 | ENSGGOP00000003761 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | 0.995 |
| IKBKG | SQSTM1 | ENSGGOP00000004800 | ENSGGOP00000020182 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Sequestosome 1. | 0.534 |