STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PI3Peptidase inhibitor 3. (117 aa)    
Predicted Functional Partners:
ENSGGOP00000046735
Non-specific serine/threonine protein kinase.
      
 0.823
WFDC8
WAP four-disulfide core domain 8.
      
 0.796
SPINT4
Serine peptidase inhibitor, Kunitz type 4.
      
 0.784
SEMG2
Semenogelin-2; Participates in the formation of a gel matrix (sperm coagulum) entrapping the accessory gland secretions and ejaculated spermatozoa.
      
 0.675
SERPINA4
Serpin family A member 4; Belongs to the serpin family.
      
 0.672
ENSGGOP00000032142
Uncharacterized protein.
      
 0.649
WFDC12
WAP four-disulfide core domain protein 12; Antibacterial protein. Putative acid-stable proteinase inhibitor (By similarity).
      
 0.647
CYTB
Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
      
 0.608
IVL
Involucrin_N domain-containing protein.
    
 0.604
G3R9L0_GORGO
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.
      
 0.569
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.