CASP3 protein (Gorilla gorilla) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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Score

CASP3

Caspase 3; Belongs to the peptidase C14A family. (277 aa)

Predicted Functional Partners:

CASP9

0.997

BIRC8

0.997

XIAP

0.997

BIRC2

0.995

PARP1

0.995

APAF1

0.995

CDKN1A

0.992

DFFA

0.991

BIRC3

0.988

BIRC7

0.981

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APAF1	BIRC2	ENSGGOP00000035421	ENSGGOP00000008137	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Baculoviral IAP repeat containing 2.	0.796
APAF1	BIRC3	ENSGGOP00000035421	ENSGGOP00000005705	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Baculoviral IAP repeat containing 3.	0.758
APAF1	BIRC7	ENSGGOP00000035421	ENSGGOP00000008152	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Baculoviral IAP repeat containing 7.	0.729
APAF1	BIRC8	ENSGGOP00000035421	ENSGGOP00000007398	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Baculoviral IAP repeat-containing protein 8; Protects against apoptosis mediated by BAX.	0.849
APAF1	CASP3	ENSGGOP00000035421	ENSGGOP00000021659	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 3; Belongs to the peptidase C14A family.	0.995
APAF1	CASP9	ENSGGOP00000035421	ENSGGOP00000001932	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 9; Belongs to the peptidase C14A family.	0.999
APAF1	DFFA	ENSGGOP00000035421	ENSGGOP00000012405	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	DNA fragmentation factor subunit alpha.	0.442
APAF1	PARP1	ENSGGOP00000035421	ENSGGOP00000025582	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.562
APAF1	XIAP	ENSGGOP00000035421	ENSGGOP00000008442	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.849
BIRC2	APAF1	ENSGGOP00000008137	ENSGGOP00000035421	Baculoviral IAP repeat containing 2.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.796
BIRC2	BIRC3	ENSGGOP00000008137	ENSGGOP00000005705	Baculoviral IAP repeat containing 2.	Baculoviral IAP repeat containing 3.	0.978
BIRC2	BIRC7	ENSGGOP00000008137	ENSGGOP00000008152	Baculoviral IAP repeat containing 2.	Baculoviral IAP repeat containing 7.	0.816
BIRC2	BIRC8	ENSGGOP00000008137	ENSGGOP00000007398	Baculoviral IAP repeat containing 2.	Baculoviral IAP repeat-containing protein 8; Protects against apoptosis mediated by BAX.	0.918
BIRC2	CASP3	ENSGGOP00000008137	ENSGGOP00000021659	Baculoviral IAP repeat containing 2.	Caspase 3; Belongs to the peptidase C14A family.	0.995
BIRC2	CASP9	ENSGGOP00000008137	ENSGGOP00000001932	Baculoviral IAP repeat containing 2.	Caspase 9; Belongs to the peptidase C14A family.	0.996
BIRC2	PARP1	ENSGGOP00000008137	ENSGGOP00000025582	Baculoviral IAP repeat containing 2.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.442
BIRC2	XIAP	ENSGGOP00000008137	ENSGGOP00000008442	Baculoviral IAP repeat containing 2.	Uncharacterized protein.	0.991
BIRC3	APAF1	ENSGGOP00000005705	ENSGGOP00000035421	Baculoviral IAP repeat containing 3.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.758
BIRC3	BIRC2	ENSGGOP00000005705	ENSGGOP00000008137	Baculoviral IAP repeat containing 3.	Baculoviral IAP repeat containing 2.	0.978
BIRC3	BIRC7	ENSGGOP00000005705	ENSGGOP00000008152	Baculoviral IAP repeat containing 3.	Baculoviral IAP repeat containing 7.	0.412