| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACAT1 | ACAT2 | ENSGGOP00000012332 | ENSGGOP00000013709 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.931 |
| ACAT1 | BDH1 | ENSGGOP00000012332 | ENSGGOP00000010891 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.573 |
| ACAT1 | EHHADH | ENSGGOP00000012332 | ENSGGOP00000007534 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.965 |
| ACAT1 | ENSGGOP00000034697 | ENSGGOP00000012332 | ENSGGOP00000034697 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Hydroxyacyl-CoA dehydrogenase. | 0.990 |
| ACAT1 | G3QFD5_GORGO | ENSGGOP00000012332 | ENSGGOP00000001004 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Acetoacetyl-CoA synthetase. | 0.943 |
| ACAT1 | HMGCL | ENSGGOP00000012332 | ENSGGOP00000004258 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.945 |
| ACAT1 | HMGCLL1 | ENSGGOP00000012332 | ENSGGOP00000048979 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Pyruvate carboxyltransferase domain-containing protein. | 0.940 |
| ACAT1 | HMGCS1 | ENSGGOP00000012332 | ENSGGOP00000001124 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.988 |
| ACAT1 | HMGCS2 | ENSGGOP00000012332 | ENSGGOP00000010047 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.989 |
| ACAT1 | OXCT1 | ENSGGOP00000012332 | ENSGGOP00000032496 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.974 |
| ACAT2 | ACAT1 | ENSGGOP00000013709 | ENSGGOP00000012332 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.931 |
| ACAT2 | EHHADH | ENSGGOP00000013709 | ENSGGOP00000007534 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.967 |
| ACAT2 | ENSGGOP00000034697 | ENSGGOP00000013709 | ENSGGOP00000034697 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Hydroxyacyl-CoA dehydrogenase. | 0.982 |
| ACAT2 | G3QFD5_GORGO | ENSGGOP00000013709 | ENSGGOP00000001004 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Acetoacetyl-CoA synthetase. | 0.939 |
| ACAT2 | HMGCL | ENSGGOP00000013709 | ENSGGOP00000004258 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.937 |
| ACAT2 | HMGCLL1 | ENSGGOP00000013709 | ENSGGOP00000048979 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Pyruvate carboxyltransferase domain-containing protein. | 0.937 |
| ACAT2 | HMGCS1 | ENSGGOP00000013709 | ENSGGOP00000001124 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.994 |
| ACAT2 | HMGCS2 | ENSGGOP00000013709 | ENSGGOP00000010047 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.985 |
| ACAT2 | OXCT1 | ENSGGOP00000013709 | ENSGGOP00000032496 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.964 |
| BDH1 | ACAT1 | ENSGGOP00000010891 | ENSGGOP00000012332 | 3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.573 |
