STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OXCT1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (557 aa)    
Predicted Functional Partners:
ACAT2
Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.967
BDH1
3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.964
HMGCL
3-hydroxy-3-methylglutaryl-CoA lyase.
  
 
 0.963
EHHADH
Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.953
HMGCLL1
Pyruvate carboxyltransferase domain-containing protein.
  
 
 0.953
ACAA2
Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.950
BDH2
3-hydroxybutyrate dehydrogenase 2.
  
 0.950
HMGCS2
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
    
 0.946
ACAA1
Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.935
HADHB
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.934
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.