PLEKHG5 protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKS6	PLEKHG5	ENSGGOP00000000371	ENSGGOP00000026688	Ankyrin repeat and sterile alpha motif domain containing 6.	Pleckstrin homology and RhoGEF domain containing G5.	0.654
FADD	G3QT76_GORGO	ENSGGOP00000020107	ENSGGOP00000005887	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.765
FADD	PLEKHG5	ENSGGOP00000020107	ENSGGOP00000026688	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Pleckstrin homology and RhoGEF domain containing G5.	0.677
FADD	RHOA	ENSGGOP00000020107	ENSGGOP00000012527	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Uncharacterized protein.	0.831
FADD	RHOC	ENSGGOP00000020107	ENSGGOP00000051168	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Ras homolog family member C.	0.682
FADD	RIPK1	ENSGGOP00000020107	ENSGGOP00000012277	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Receptor interacting serine/threonine kinase 1.	0.999
FADD	TRADD	ENSGGOP00000020107	ENSGGOP00000011592	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Death domain-containing protein.	0.999
G3QT76_GORGO	FADD	ENSGGOP00000005887	ENSGGOP00000020107	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.765
G3QT76_GORGO	PLEKHG5	ENSGGOP00000005887	ENSGGOP00000026688	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Pleckstrin homology and RhoGEF domain containing G5.	0.746
G3QT76_GORGO	RIPK1	ENSGGOP00000005887	ENSGGOP00000012277	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Receptor interacting serine/threonine kinase 1.	0.980
G3QT76_GORGO	TRADD	ENSGGOP00000005887	ENSGGOP00000011592	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Death domain-containing protein.	0.979
PLEKHG5	ANKS6	ENSGGOP00000026688	ENSGGOP00000000371	Pleckstrin homology and RhoGEF domain containing G5.	Ankyrin repeat and sterile alpha motif domain containing 6.	0.654
PLEKHG5	FADD	ENSGGOP00000026688	ENSGGOP00000020107	Pleckstrin homology and RhoGEF domain containing G5.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.677
PLEKHG5	G3QT76_GORGO	ENSGGOP00000026688	ENSGGOP00000005887	Pleckstrin homology and RhoGEF domain containing G5.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.746
PLEKHG5	RHOA	ENSGGOP00000026688	ENSGGOP00000012527	Pleckstrin homology and RhoGEF domain containing G5.	Uncharacterized protein.	0.755
PLEKHG5	RHOC	ENSGGOP00000026688	ENSGGOP00000051168	Pleckstrin homology and RhoGEF domain containing G5.	Ras homolog family member C.	0.652
PLEKHG5	RIPK1	ENSGGOP00000026688	ENSGGOP00000012277	Pleckstrin homology and RhoGEF domain containing G5.	Receptor interacting serine/threonine kinase 1.	0.691
PLEKHG5	RND1	ENSGGOP00000026688	ENSGGOP00000006914	Pleckstrin homology and RhoGEF domain containing G5.	Rho family GTPase 1.	0.766
PLEKHG5	RND3	ENSGGOP00000026688	ENSGGOP00000038343	Pleckstrin homology and RhoGEF domain containing G5.	Rho family GTPase 3.	0.925
PLEKHG5	TNFSF15	ENSGGOP00000026688	ENSGGOP00000010545	Pleckstrin homology and RhoGEF domain containing G5.	TNF superfamily member 15.	0.798