STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)    
Predicted Functional Partners:
ITGB7
Integrin beta; Belongs to the integrin beta chain family.
   
 0.999
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.999
VCAM1
Vascular cell adhesion molecule 1.
   
 0.994
JAM2
Junctional adhesion molecule 2.
     
 0.974
SPP1
Secreted phosphoprotein 1.
   
 0.972
ITGA5
Integrin subunit alpha 5; Belongs to the integrin alpha chain family.
    
0.965
ENSGGOP00000044113
Uncharacterized protein.
    
 0.952
SRC
Tyrosine-protein kinase.
   
 0.946
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.942
ENSGGOP00000042710
Integrin beta.
   
 0.940
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.