STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRG1Neuregulin 1. (713 aa)    
Predicted Functional Partners:
ERBB4
Receptor protein-tyrosine kinase.
    
 0.997
ERBB2
Receptor protein-tyrosine kinase.
    
 0.992
ERBB3
Protein kinase domain-containing protein.
    
 0.989
EGFR
Receptor protein-tyrosine kinase.
    
 0.977
NRG4
Neuregulin 4.
    
 0.941
NRG3
Neuregulin 3.
     
0.916
ENSGGOP00000034632
Recep_L_domain domain-containing protein.
    
 0.895
PRSS12
Neurotrypsin; Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations; Belongs to the peptidase S1 family.
    
 0.690
RNF41
Ring finger protein 41.
    
 0.641
EPHB2
EPH receptor B2.
   
 0.635
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.