STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP15Poly [ADP-ribose] polymerase. (678 aa)    
Predicted Functional Partners:
PARP4
Poly [ADP-ribose] polymerase.
    
 
 0.674
IFIH1
Interferon induced with helicase C domain 1.
   
 
 0.660
PARP9
Poly(ADP-ribose) polymerase family member 9.
  
 
0.655
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
   
 
 0.622
RNF213
Ring finger protein 213.
   
 0.617
PARP16
Poly [ADP-ribose] polymerase.
      
 0.571
PARP3
Poly [ADP-ribose] polymerase.
    
 
 0.563
PARP2
Poly [ADP-ribose] polymerase.
   
 
 0.539
STAT1
Signal transducer and activator of transcription.
   
 
 0.523
TEP1
Telomerase associated protein 1.
      
 0.518
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.