STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa)    
Predicted Functional Partners:
RRM2
Ribonucleotide reductase regulatory subunit M2.
  
 0.999
RRM2B
LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase subunit M2 B.
  
 0.998
G3QKM4_GORGO
Ribonucleotide reductase regulatory TP53 inducible subunit M2B.
  
 0.988
NTPCR
AAA domain-containing protein.
     
  0.981
ENSGGOP00000048702
Uncharacterized protein.
  
 0.966
DTYMK
Deoxythymidylate kinase.
  
 
 0.958
CMPK2
Uncharacterized protein.
  
 
 0.958
CMPK1
Uncharacterized protein; Belongs to the adenylate kinase family.
    
 0.957
AK3
GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
    
 0.952
GUK1
Guanylate kinase-like domain-containing protein.
     
 0.952
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.