STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)    
Predicted Functional Partners:
ERN1
Endoplasmic reticulum to nucleus signaling 1.
    
 0.999
EIF2AK3
Eukaryotic translation initiation factor 2 alpha kinase 3.
   
 0.999
ATF6
Activating transcription factor 6.
    
 0.999
HYOU1
Hypoxia up-regulated 1.
  
0.988
DNAJB11
J domain-containing protein.
 
 0.986
DNAJC10
DnaJ heat shock protein family (Hsp40) member C10.
  
 0.974
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.965
MANF
Mesencephalic astrocyte derived neurotrophic factor.
   
 
 0.961
SOD1
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 0.959
CANX
Calnexin.
   
 0.951
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.