STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3S7H0_GORGOAdaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (646 aa)    
Predicted Functional Partners:
RAB5A
RAB5A, member RAS oncogene family.
   
 
 0.980
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
  
 
0.953
ENSGGOP00000046735
Non-specific serine/threonine protein kinase.
    
 
 0.929
ITSN2
Intersectin 2.
   
 0.909
DCC
DCC netrin 1 receptor.
   
 0.900
G3SG23_GORGO
Neogenin 1.
   
 0.900
IGDCC3
Immunoglobulin superfamily DCC subclass member 3.
   
  0.896
IGDCC4
Immunoglobulin superfamily DCC subclass member 4.
   
  0.896
FNDC1
Fibronectin type III domain containing 1.
    
  0.894
GIPC1
GIPC PDZ domain containing family member 1.
   
 
 0.892
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.