GTF2E2 protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSGGOP00000029268	ERCC2	ENSGGOP00000029268	ENSGGOP00000050930	Uncharacterized protein.	ERCC excision repair 2, TFIIH core complex helicase subunit.	0.986
ENSGGOP00000029268	ERCC3	ENSGGOP00000029268	ENSGGOP00000014886	Uncharacterized protein.	ERCC excision repair 3, TFIIH core complex helicase subunit.	0.986
ENSGGOP00000029268	GTF2A1	ENSGGOP00000029268	ENSGGOP00000003212	Uncharacterized protein.	General transcription factor IIA subunit 1.	0.890
ENSGGOP00000029268	GTF2B	ENSGGOP00000029268	ENSGGOP00000020269	Uncharacterized protein.	General transcription factor IIB.	0.924
ENSGGOP00000029268	GTF2E1	ENSGGOP00000029268	ENSGGOP00000021689	Uncharacterized protein.	General transcription factor IIE subunit 1.	0.963
ENSGGOP00000029268	GTF2E2	ENSGGOP00000029268	ENSGGOP00000021323	Uncharacterized protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.967
ENSGGOP00000029268	GTF2F1	ENSGGOP00000029268	ENSGGOP00000046119	Uncharacterized protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.921
ENSGGOP00000029268	GTF2H3	ENSGGOP00000029268	ENSGGOP00000008967	Uncharacterized protein.	General transcription factor IIH subunit 3.	0.998
ENSGGOP00000029268	GTF2H4	ENSGGOP00000029268	ENSGGOP00000013896	Uncharacterized protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.998
ENSGGOP00000029268	MNAT1	ENSGGOP00000029268	ENSGGOP00000008915	Uncharacterized protein.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.957
ERCC2	ENSGGOP00000029268	ENSGGOP00000050930	ENSGGOP00000029268	ERCC excision repair 2, TFIIH core complex helicase subunit.	Uncharacterized protein.	0.986
ERCC2	ERCC3	ENSGGOP00000050930	ENSGGOP00000014886	ERCC excision repair 2, TFIIH core complex helicase subunit.	ERCC excision repair 3, TFIIH core complex helicase subunit.	0.998
ERCC2	GTF2A1	ENSGGOP00000050930	ENSGGOP00000003212	ERCC excision repair 2, TFIIH core complex helicase subunit.	General transcription factor IIA subunit 1.	0.891
ERCC2	GTF2B	ENSGGOP00000050930	ENSGGOP00000020269	ERCC excision repair 2, TFIIH core complex helicase subunit.	General transcription factor IIB.	0.936
ERCC2	GTF2E1	ENSGGOP00000050930	ENSGGOP00000021689	ERCC excision repair 2, TFIIH core complex helicase subunit.	General transcription factor IIE subunit 1.	0.951
ERCC2	GTF2E2	ENSGGOP00000050930	ENSGGOP00000021323	ERCC excision repair 2, TFIIH core complex helicase subunit.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.954
ERCC2	GTF2F1	ENSGGOP00000050930	ENSGGOP00000046119	ERCC excision repair 2, TFIIH core complex helicase subunit.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.923
ERCC2	GTF2H3	ENSGGOP00000050930	ENSGGOP00000008967	ERCC excision repair 2, TFIIH core complex helicase subunit.	General transcription factor IIH subunit 3.	0.995
ERCC2	GTF2H4	ENSGGOP00000050930	ENSGGOP00000013896	ERCC excision repair 2, TFIIH core complex helicase subunit.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.985
ERCC2	MNAT1	ENSGGOP00000050930	ENSGGOP00000008915	ERCC excision repair 2, TFIIH core complex helicase subunit.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.987