STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAPN1Calpain 1; Belongs to the peptidase C2 family. (729 aa)    
Predicted Functional Partners:
CAPNS1
Calpain small subunit 1.
   
0.988
CAST
Calpastatin.
   
 0.978
CDK5R1
Cyclin-dependent kinase 5 activator.
   
 
 0.949
G3R8R1_GORGO
Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family.
   
 0.924
BAK1
BCL2 antagonist/killer 1.
   
 0.923
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
  0.909
IL1A
Interleukin-1; Belongs to the IL-1 family.
   
 
 0.906
BAX
BCL2 associated X, apoptosis regulator.
   
  0.906
ENSGGOP00000030133
Calpain 8; Belongs to the peptidase C2 family.
  
0.775
G3QYC6_GORGO
Calpain 2; Belongs to the peptidase C2 family.
  
0.725
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.