PGR protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ESR1	FKBP4	ENSGGOP00000009454	ENSGGOP00000010216	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Peptidylprolyl isomerase.	0.645
ESR1	FKBP5	ENSGGOP00000009454	ENSGGOP00000005256	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Peptidylprolyl isomerase.	0.631
ESR1	G3R9L0_GORGO	ENSGGOP00000009454	ENSGGOP00000012094	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	0.709
ESR1	NCOA1	ENSGGOP00000009454	ENSGGOP00000011007	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor coactivator.	0.997
ESR1	NCOA3	ENSGGOP00000009454	ENSGGOP00000019561	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor coactivator.	0.999
ESR1	PGR	ENSGGOP00000009454	ENSGGOP00000024814	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.	0.987
ESR1	PIK3CA	ENSGGOP00000009454	ENSGGOP00000009158	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.923
ESR1	PIK3CB	ENSGGOP00000009454	ENSGGOP00000009368	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.710
ESR1	PIK3R1	ENSGGOP00000009454	ENSGGOP00000050489	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Phosphoinositide-3-kinase regulatory subunit 1.	0.930
ESR1	SRC	ENSGGOP00000009454	ENSGGOP00000018321	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Tyrosine-protein kinase.	0.997
FKBP4	ESR1	ENSGGOP00000010216	ENSGGOP00000009454	Peptidylprolyl isomerase.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.645
FKBP4	FKBP5	ENSGGOP00000010216	ENSGGOP00000005256	Peptidylprolyl isomerase.	Peptidylprolyl isomerase.	0.995
FKBP4	PGR	ENSGGOP00000010216	ENSGGOP00000024814	Peptidylprolyl isomerase.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.	0.964
FKBP5	ESR1	ENSGGOP00000005256	ENSGGOP00000009454	Peptidylprolyl isomerase.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.631
FKBP5	FKBP4	ENSGGOP00000005256	ENSGGOP00000010216	Peptidylprolyl isomerase.	Peptidylprolyl isomerase.	0.995
FKBP5	PGR	ENSGGOP00000005256	ENSGGOP00000024814	Peptidylprolyl isomerase.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.	0.934
G3R9L0_GORGO	ESR1	ENSGGOP00000012094	ENSGGOP00000009454	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.709
G3R9L0_GORGO	PGR	ENSGGOP00000012094	ENSGGOP00000024814	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.	0.937
G3R9L0_GORGO	PIK3CA	ENSGGOP00000012094	ENSGGOP00000009158	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.985
G3R9L0_GORGO	PIK3CB	ENSGGOP00000012094	ENSGGOP00000009368	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.973