STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDIA3Protein disulfide-isomerase. (383 aa)    
Predicted Functional Partners:
CALR
Calreticulin.
   
 0.998
TAPBP
TAP binding protein.
   
 0.996
TAP1
Antigen peptide transporter 1; Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin (By similarity); Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
   
 0.962
CANX
Calnexin.
   
 0.952
G3RAL4_GORGO
Major histocompatibility complex, class I, E; Belongs to the MHC class I family.
    
 0.950
G3R3J7_GORGO
MHC_I-like_Ag-recog domain-containing protein.
    
 0.946
TAP2
Transporter 2, ATP binding cassette subfamily B member.
   
 0.946
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
 0.925
G3QYA4_GORGO
Major histocompatibility complex, class I, G; Belongs to the MHC class I family.
    
  0.924
CALR3
Calreticulin.
   
 0.902
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.