PRKACB protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKAP1	ENSGGOP00000032040	ENSGGOP00000023166	ENSGGOP00000032040	A-kinase anchoring protein 1.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.984
AKAP1	PDE4A	ENSGGOP00000023166	ENSGGOP00000030052	A-kinase anchoring protein 1.	Phosphodiesterase.	0.466
AKAP1	PRKACB	ENSGGOP00000023166	ENSGGOP00000025699	A-kinase anchoring protein 1.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.984
AKAP1	PRKAR1A	ENSGGOP00000023166	ENSGGOP00000050401	A-kinase anchoring protein 1.	Protein kinase cAMP-dependent type I regulatory subunit alpha.	0.863
AKAP1	PRKAR1B	ENSGGOP00000023166	ENSGGOP00000011641	A-kinase anchoring protein 1.	Protein kinase cAMP-dependent type I regulatory subunit beta.	0.776
AKAP1	PRKAR2A	ENSGGOP00000023166	ENSGGOP00000008988	A-kinase anchoring protein 1.	Protein kinase cAMP-dependent type II regulatory subunit alpha.	0.968
AKAP1	PRKAR2B	ENSGGOP00000023166	ENSGGOP00000042112	A-kinase anchoring protein 1.	Protein kinase cAMP-dependent type II regulatory subunit beta.	0.953
ENSGGOP00000032040	AKAP1	ENSGGOP00000032040	ENSGGOP00000023166	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	A-kinase anchoring protein 1.	0.984
ENSGGOP00000032040	ENSGGOP00000032619	ENSGGOP00000032040	ENSGGOP00000032619	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	cAMP responsive element binding protein 1.	0.992
ENSGGOP00000032040	PDE4A	ENSGGOP00000032040	ENSGGOP00000030052	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	Phosphodiesterase.	0.980
ENSGGOP00000032040	PLN	ENSGGOP00000032040	ENSGGOP00000049438	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.	0.984
ENSGGOP00000032040	PPP1R1B	ENSGGOP00000032040	ENSGGOP00000006601	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	Protein phosphatase 1 regulatory inhibitor subunit 1B.	0.988
ENSGGOP00000032040	PRKACB	ENSGGOP00000032040	ENSGGOP00000025699	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.999
ENSGGOP00000032040	PRKAR1A	ENSGGOP00000032040	ENSGGOP00000050401	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	Protein kinase cAMP-dependent type I regulatory subunit alpha.	0.999
ENSGGOP00000032040	PRKAR1B	ENSGGOP00000032040	ENSGGOP00000011641	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	Protein kinase cAMP-dependent type I regulatory subunit beta.	0.999
ENSGGOP00000032040	PRKAR2A	ENSGGOP00000032040	ENSGGOP00000008988	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	Protein kinase cAMP-dependent type II regulatory subunit alpha.	0.997
ENSGGOP00000032040	PRKAR2B	ENSGGOP00000032040	ENSGGOP00000042112	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	Protein kinase cAMP-dependent type II regulatory subunit beta.	0.998
ENSGGOP00000032619	ENSGGOP00000032040	ENSGGOP00000032619	ENSGGOP00000032040	cAMP responsive element binding protein 1.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.992
ENSGGOP00000032619	PRKACB	ENSGGOP00000032619	ENSGGOP00000025699	cAMP responsive element binding protein 1.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.986
PDE4A	AKAP1	ENSGGOP00000030052	ENSGGOP00000023166	Phosphodiesterase.	A-kinase anchoring protein 1.	0.466