| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DCAKD | OSGEP | ENSGGOP00000009345 | ENSGGOP00000002091 | Dephospho-CoA kinase domain containing. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.598 |
| DCAKD | OSGEPL1 | ENSGGOP00000009345 | ENSGGOP00000025819 | Dephospho-CoA kinase domain containing. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.598 |
| ENSGGOP00000041239 | OSGEPL1 | ENSGGOP00000041239 | ENSGGOP00000025819 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.627 |
| ENSGGOP00000041239 | TRIT1 | ENSGGOP00000041239 | ENSGGOP00000009829 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. | 0.581 |
| ENSGGOP00000041239 | YRDC | ENSGGOP00000041239 | ENSGGOP00000007452 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | YrdC N6-threonylcarbamoyltransferase domain containing. | 0.651 |
| G3R110_GORGO | GON7 | ENSGGOP00000008859 | ENSGGOP00000019470 | TP53RK binding protein; Belongs to the CGI121/TPRKB family. | GON7 subunit of KEOPS complex. | 0.907 |
| G3R110_GORGO | OSGEP | ENSGGOP00000008859 | ENSGGOP00000002091 | TP53RK binding protein; Belongs to the CGI121/TPRKB family. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.990 |
| G3R110_GORGO | OSGEPL1 | ENSGGOP00000008859 | ENSGGOP00000025819 | TP53RK binding protein; Belongs to the CGI121/TPRKB family. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.827 |
| G3R110_GORGO | TP53RK | ENSGGOP00000008859 | ENSGGOP00000002031 | TP53RK binding protein; Belongs to the CGI121/TPRKB family. | TP53 regulating kinase. | 0.999 |
| G3R110_GORGO | YRDC | ENSGGOP00000008859 | ENSGGOP00000007452 | TP53RK binding protein; Belongs to the CGI121/TPRKB family. | YrdC N6-threonylcarbamoyltransferase domain containing. | 0.525 |
| G3RHR9_GORGO | OSGEP | ENSGGOP00000015197 | ENSGGOP00000002091 | Acid phosphatase 1. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.622 |
| G3RHR9_GORGO | OSGEPL1 | ENSGGOP00000015197 | ENSGGOP00000025819 | Acid phosphatase 1. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.622 |
| GON7 | G3R110_GORGO | ENSGGOP00000019470 | ENSGGOP00000008859 | GON7 subunit of KEOPS complex. | TP53RK binding protein; Belongs to the CGI121/TPRKB family. | 0.907 |
| GON7 | OSGEP | ENSGGOP00000019470 | ENSGGOP00000002091 | GON7 subunit of KEOPS complex. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.997 |
| GON7 | OSGEPL1 | ENSGGOP00000019470 | ENSGGOP00000025819 | GON7 subunit of KEOPS complex. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.793 |
| GON7 | TP53RK | ENSGGOP00000019470 | ENSGGOP00000002031 | GON7 subunit of KEOPS complex. | TP53 regulating kinase. | 0.997 |
| GON7 | YRDC | ENSGGOP00000019470 | ENSGGOP00000007452 | GON7 subunit of KEOPS complex. | YrdC N6-threonylcarbamoyltransferase domain containing. | 0.473 |
| OSGEP | DCAKD | ENSGGOP00000002091 | ENSGGOP00000009345 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Dephospho-CoA kinase domain containing. | 0.598 |
| OSGEP | G3R110_GORGO | ENSGGOP00000002091 | ENSGGOP00000008859 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | TP53RK binding protein; Belongs to the CGI121/TPRKB family. | 0.990 |
| OSGEP | G3RHR9_GORGO | ENSGGOP00000002091 | ENSGGOP00000015197 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Acid phosphatase 1. | 0.622 |
