| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| COASY | DCAKD | ENSGGOP00000010586 | ENSGGOP00000009345 | Coenzyme A synthase. | Dephospho-CoA kinase domain containing. | 0.853 |
| COASY | OSGEP | ENSGGOP00000010586 | ENSGGOP00000002091 | Coenzyme A synthase. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.570 |
| COASY | OSGEPL1 | ENSGGOP00000010586 | ENSGGOP00000025819 | Coenzyme A synthase. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.570 |
| DCAKD | COASY | ENSGGOP00000009345 | ENSGGOP00000010586 | Dephospho-CoA kinase domain containing. | Coenzyme A synthase. | 0.853 |
| DCAKD | OSGEP | ENSGGOP00000009345 | ENSGGOP00000002091 | Dephospho-CoA kinase domain containing. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.570 |
| DCAKD | OSGEPL1 | ENSGGOP00000009345 | ENSGGOP00000025819 | Dephospho-CoA kinase domain containing. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.570 |
| EPRS1 | OSGEP | ENSGGOP00000012123 | ENSGGOP00000002091 | Glutamyl-prolyl-tRNA synthetase. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.537 |
| EPRS1 | OSGEPL1 | ENSGGOP00000012123 | ENSGGOP00000025819 | Glutamyl-prolyl-tRNA synthetase. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.528 |
| EPRS1 | YRDC | ENSGGOP00000012123 | ENSGGOP00000007452 | Glutamyl-prolyl-tRNA synthetase. | YrdC N6-threonylcarbamoyltransferase domain containing. | 0.504 |
| G3R110_GORGO | GON7 | ENSGGOP00000008859 | ENSGGOP00000019470 | TP53RK binding protein; Belongs to the CGI121/TPRKB family. | GON7 subunit of KEOPS complex. | 0.929 |
| G3R110_GORGO | OSGEP | ENSGGOP00000008859 | ENSGGOP00000002091 | TP53RK binding protein; Belongs to the CGI121/TPRKB family. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.998 |
| G3R110_GORGO | OSGEPL1 | ENSGGOP00000008859 | ENSGGOP00000025819 | TP53RK binding protein; Belongs to the CGI121/TPRKB family. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.937 |
| G3R110_GORGO | TP53RK | ENSGGOP00000008859 | ENSGGOP00000002031 | TP53RK binding protein; Belongs to the CGI121/TPRKB family. | TP53 regulating kinase. | 0.999 |
| G3R110_GORGO | YRDC | ENSGGOP00000008859 | ENSGGOP00000007452 | TP53RK binding protein; Belongs to the CGI121/TPRKB family. | YrdC N6-threonylcarbamoyltransferase domain containing. | 0.619 |
| G3RHR9_GORGO | OSGEP | ENSGGOP00000015197 | ENSGGOP00000002091 | Acid phosphatase 1. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.799 |
| G3RHR9_GORGO | OSGEPL1 | ENSGGOP00000015197 | ENSGGOP00000025819 | Acid phosphatase 1. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.799 |
| GON7 | G3R110_GORGO | ENSGGOP00000019470 | ENSGGOP00000008859 | GON7 subunit of KEOPS complex. | TP53RK binding protein; Belongs to the CGI121/TPRKB family. | 0.929 |
| GON7 | OSGEP | ENSGGOP00000019470 | ENSGGOP00000002091 | GON7 subunit of KEOPS complex. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.992 |
| GON7 | OSGEPL1 | ENSGGOP00000019470 | ENSGGOP00000025819 | GON7 subunit of KEOPS complex. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.849 |
| GON7 | TP53RK | ENSGGOP00000019470 | ENSGGOP00000002031 | GON7 subunit of KEOPS complex. | TP53 regulating kinase. | 0.987 |