STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB14Growth factor receptor bound protein 14. (476 aa)    
Predicted Functional Partners:
INSR
Tyrosine-protein kinase receptor.
    
 0.983
HRAS
HRas proto-oncogene, GTPase.
    
 0.877
FGFR1
Fibroblast growth factor receptor.
    
 0.801
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
   
 
 0.725
PERP
P53 apoptosis effector related to PMP22.
      
 0.710
SREBF1
Sterol regulatory element binding transcription factor 1.
      
 0.710
G3RT31_GORGO
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.
      
 0.697
CEACAM7
Carcinoembryonic antigen related cell adhesion molecule 7.
    
 
 0.691
IGF1R
Tyrosine-protein kinase receptor.
    
 0.682
LY75
Uncharacterized protein.
      
 0.672
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.