G3SD87_GORGO protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO2	DCP1A	ENSGGOP00000011130	ENSGGOP00000012503	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Decapping mRNA 1A.	0.418
AGO2	DCP2	ENSGGOP00000011130	ENSGGOP00000024475	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Decapping mRNA 2.	0.644
AGO2	G3RDD0_GORGO	ENSGGOP00000011130	ENSGGOP00000013531	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Enhancer of mRNA decapping 4.	0.566
AGO2	G3SAS0_GORGO	ENSGGOP00000011130	ENSGGOP00000025193	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Ataxin 2.	0.638
AGO2	G3SD87_GORGO	ENSGGOP00000011130	ENSGGOP00000026066	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.962
DCP1A	AGO2	ENSGGOP00000012503	ENSGGOP00000011130	Decapping mRNA 1A.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.418
DCP1A	DCP1B	ENSGGOP00000012503	ENSGGOP00000023512	Decapping mRNA 1A.	Decapping mRNA 1B.	0.998
DCP1A	DCP2	ENSGGOP00000012503	ENSGGOP00000024475	Decapping mRNA 1A.	Decapping mRNA 2.	0.998
DCP1A	EDC3	ENSGGOP00000012503	ENSGGOP00000003490	Decapping mRNA 1A.	Enhancer of mRNA decapping 3.	0.996
DCP1A	G3RDD0_GORGO	ENSGGOP00000012503	ENSGGOP00000013531	Decapping mRNA 1A.	Enhancer of mRNA decapping 4.	0.997
DCP1A	G3SAS0_GORGO	ENSGGOP00000012503	ENSGGOP00000025193	Decapping mRNA 1A.	Ataxin 2.	0.469
DCP1A	G3SD87_GORGO	ENSGGOP00000012503	ENSGGOP00000026066	Decapping mRNA 1A.	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.991
DCP1A	LSM14A	ENSGGOP00000012503	ENSGGOP00000043549	Decapping mRNA 1A.	Uncharacterized protein.	0.816
DCP1A	PATL1	ENSGGOP00000012503	ENSGGOP00000004256	Decapping mRNA 1A.	PAT1 homolog 1, processing body mRNA decay factor.	0.962
DCP1B	DCP1A	ENSGGOP00000023512	ENSGGOP00000012503	Decapping mRNA 1B.	Decapping mRNA 1A.	0.998
DCP1B	DCP2	ENSGGOP00000023512	ENSGGOP00000024475	Decapping mRNA 1B.	Decapping mRNA 2.	0.993
DCP1B	EDC3	ENSGGOP00000023512	ENSGGOP00000003490	Decapping mRNA 1B.	Enhancer of mRNA decapping 3.	0.991
DCP1B	G3RDD0_GORGO	ENSGGOP00000023512	ENSGGOP00000013531	Decapping mRNA 1B.	Enhancer of mRNA decapping 4.	0.984
DCP1B	G3SAS0_GORGO	ENSGGOP00000023512	ENSGGOP00000025193	Decapping mRNA 1B.	Ataxin 2.	0.464
DCP1B	G3SD87_GORGO	ENSGGOP00000023512	ENSGGOP00000026066	Decapping mRNA 1B.	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.980