STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERPINB4Serpin family B member 4; Belongs to the serpin family. (390 aa)    
Predicted Functional Partners:
KLK5
Kallikrein related peptidase 5; Belongs to the peptidase S1 family.
   
 0.701
G3RJL3_GORGO
Keratin 81; Belongs to the intermediate filament family.
     
 0.697
G3QQE4_GORGO
Uncharacterized protein; Belongs to the peptidase C1 family.
    
 0.634
CTRL
Chymotrypsin like; Belongs to the peptidase S1 family.
    
 0.623
G3SEM1_GORGO
Cathepsin L; Belongs to the peptidase C1 family.
   
 0.612
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.609
CMA1
Chymase 1; Belongs to the peptidase S1 family.
    
 0.554
G3RD46_GORGO
Cathepsin G; Belongs to the peptidase S1 family.
    
 0.548
G3QUU9_GORGO
Protein S100; Belongs to the S-100 family.
   
 0.546
G3R6P6_GORGO
Kallikrein related peptidase 6; Belongs to the peptidase S1 family.
    
 0.526
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.