STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa)    
Predicted Functional Partners:
ENSGGOP00000043083
Nuclear receptor corepressor 2.
   
 0.983
ANKRA2
Ankyrin repeat family A member 2.
    
 0.974
ENSGGOP00000038823
Nuclear receptor corepressor 1.
    
 0.971
YWHAG
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family.
    
 
 0.949
ENSGGOP00000031261
Myocyte enhancer factor 2C.
   
 
 0.948
HDAC5
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
  
 
0.944
RUNX2
Runt domain-containing protein.
   
 0.943
CAMK4
Calcium/calmodulin dependent protein kinase IV.
   
 0.936
RFXANK
Regulatory factor X associated ankyrin containing protein.
   
 0.914
MEF2A
Myocyte enhancer factor 2A.
   
 
 0.913
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: medium (54%) [HD]