| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CGA | CGB2 | ENSGGOP00000030475 | ENSGGOP00000006854 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Chorionic gonadotropin subunit beta 2. | 0.870 |
| CGA | ENSGGOP00000038559 | ENSGGOP00000030475 | ENSGGOP00000038559 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Cys_knot domain-containing protein. | 0.870 |
| CGA | ENSGGOP00000041788 | ENSGGOP00000030475 | ENSGGOP00000041788 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Cys_knot domain-containing protein. | 0.870 |
| CGA | FANCM | ENSGGOP00000030475 | ENSGGOP00000008369 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | FA complementation group M. | 0.891 |
| CGA | FSHB | ENSGGOP00000030475 | ENSGGOP00000017457 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | 0.998 |
| CGA | GPHA2 | ENSGGOP00000030475 | ENSGGOP00000000355 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Glycoprotein hormone subunit alpha 2. | 0.815 |
| CGA | LHB | ENSGGOP00000030475 | ENSGGOP00000009057 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. | 0.870 |
| CGA | POMC | ENSGGOP00000030475 | ENSGGOP00000003417 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Proopiomelanocortin. | 0.827 |
| CGA | TSHB | ENSGGOP00000030475 | ENSGGOP00000010131 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Thyroid stimulating hormone subunit beta. | 0.992 |
| CGA | TSHR | ENSGGOP00000030475 | ENSGGOP00000018300 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.810 |
| CGB2 | CGA | ENSGGOP00000006854 | ENSGGOP00000030475 | Chorionic gonadotropin subunit beta 2. | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | 0.870 |
| CGB2 | TSHR | ENSGGOP00000006854 | ENSGGOP00000018300 | Chorionic gonadotropin subunit beta 2. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.580 |
| ENSGGOP00000038559 | CGA | ENSGGOP00000038559 | ENSGGOP00000030475 | Cys_knot domain-containing protein. | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | 0.870 |
| ENSGGOP00000038559 | TSHR | ENSGGOP00000038559 | ENSGGOP00000018300 | Cys_knot domain-containing protein. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.464 |
| ENSGGOP00000041788 | CGA | ENSGGOP00000041788 | ENSGGOP00000030475 | Cys_knot domain-containing protein. | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | 0.870 |
| ENSGGOP00000041788 | TSHR | ENSGGOP00000041788 | ENSGGOP00000018300 | Cys_knot domain-containing protein. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.464 |
| FANCM | CGA | ENSGGOP00000008369 | ENSGGOP00000030475 | FA complementation group M. | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | 0.891 |
| FSHB | CGA | ENSGGOP00000017457 | ENSGGOP00000030475 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | 0.998 |
| FSHB | POMC | ENSGGOP00000017457 | ENSGGOP00000003417 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Proopiomelanocortin. | 0.647 |
| FSHB | TSHB | ENSGGOP00000017457 | ENSGGOP00000010131 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Thyroid stimulating hormone subunit beta. | 0.452 |
