close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUL5Cullin 5; Belongs to the cullin family. (780 aa)    
Predicted Functional Partners:
RNF7
Ring finger protein 7.
    
 0.999
ELOC
Elongin C; Belongs to the SKP1 family.
    
 0.999
G3QLU7_GORGO
RING-type domain-containing protein.
    
 0.999
G3R2E6_GORGO
Skp1_POZ domain-containing protein; Belongs to the SKP1 family.
    
 0.999
ELOB
Elongin B.
    
 0.999
CBFB
Core-binding factor subunit beta.
    
 
 0.995
NEDD8
NEDD8 ubiquitin like modifier.
    
 0.991
SOCS2
Suppressor of cytokine signaling 2.
   
 0.988
ENSGGOP00000045589
Ubiquitin-like domain-containing protein.
    
 0.978
APOBEC3G
DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...]
     
 0.976
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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