STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IST1Uncharacterized protein. (343 aa)    
Predicted Functional Partners:
SPAST
AAA domain-containing protein; Belongs to the AAA ATPase family.
    
 0.966
VPS4B
Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.
   
 0.960
VTA1
Vesicle trafficking 1.
   
 
 0.929
G3R937_GORGO
Charged multivesicular body protein 1A.
    
 
 0.926
VPS4A
Uncharacterized protein; Belongs to the AAA ATPase family.
   
 0.906
CHMP2A
Charged multivesicular body protein 2A.
    
 0.900
CHMP6
Uncharacterized protein.
    
 0.886
SPART
Spartin.
    
 
 0.879
ULK3
Unc-51 like kinase 3.
    
 
 0.856
CHMP4C
Charged multivesicular body protein 4C.
    
 0.809
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.