RAB5C protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RAB5C

RAB5C, member RAS oncogene family. (249 aa)

Predicted Functional Partners:

RAB5A

0.988

PIK3C3

0.955

EEA1

0.954

RIN1

0.939

G3R475_GORGO

0.896

G3RTS2_GORGO

0.896

ENSGGOP00000052295

0.896

GDI2

0.831

ENSGGOP00000032505

0.806

GDI1

0.800

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEA1	ENSGGOP00000052295	ENSGGOP00000005133	ENSGGOP00000052295	Early endosome antigen 1.	A20-type domain-containing protein.	0.736
EEA1	G3R475_GORGO	ENSGGOP00000005133	ENSGGOP00000010066	Early endosome antigen 1.	RAB guanine nucleotide exchange factor 1.	0.790
EEA1	G3RTS2_GORGO	ENSGGOP00000005133	ENSGGOP00000019199	Early endosome antigen 1.	A20-type domain-containing protein.	0.790
EEA1	PIK3C3	ENSGGOP00000005133	ENSGGOP00000036428	Early endosome antigen 1.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.943
EEA1	RAB5A	ENSGGOP00000005133	ENSGGOP00000015584	Early endosome antigen 1.	RAB5A, member RAS oncogene family.	0.999
EEA1	RAB5C	ENSGGOP00000005133	ENSGGOP00000048837	Early endosome antigen 1.	RAB5C, member RAS oncogene family.	0.954
EEA1	RIN1	ENSGGOP00000005133	ENSGGOP00000010249	Early endosome antigen 1.	Ras and Rab interactor 1.	0.493
ENSGGOP00000032505	ENSGGOP00000052295	ENSGGOP00000032505	ENSGGOP00000052295	Uncharacterized protein.	A20-type domain-containing protein.	0.685
ENSGGOP00000032505	G3R475_GORGO	ENSGGOP00000032505	ENSGGOP00000010066	Uncharacterized protein.	RAB guanine nucleotide exchange factor 1.	0.685
ENSGGOP00000032505	G3RTS2_GORGO	ENSGGOP00000032505	ENSGGOP00000019199	Uncharacterized protein.	A20-type domain-containing protein.	0.685
ENSGGOP00000032505	GDI1	ENSGGOP00000032505	ENSGGOP00000013144	Uncharacterized protein.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.771
ENSGGOP00000032505	RAB5A	ENSGGOP00000032505	ENSGGOP00000015584	Uncharacterized protein.	RAB5A, member RAS oncogene family.	0.817
ENSGGOP00000032505	RAB5C	ENSGGOP00000032505	ENSGGOP00000048837	Uncharacterized protein.	RAB5C, member RAS oncogene family.	0.806
ENSGGOP00000052295	EEA1	ENSGGOP00000052295	ENSGGOP00000005133	A20-type domain-containing protein.	Early endosome antigen 1.	0.736
ENSGGOP00000052295	ENSGGOP00000032505	ENSGGOP00000052295	ENSGGOP00000032505	A20-type domain-containing protein.	Uncharacterized protein.	0.685
ENSGGOP00000052295	G3R475_GORGO	ENSGGOP00000052295	ENSGGOP00000010066	A20-type domain-containing protein.	RAB guanine nucleotide exchange factor 1.	0.537
ENSGGOP00000052295	G3RTS2_GORGO	ENSGGOP00000052295	ENSGGOP00000019199	A20-type domain-containing protein.	A20-type domain-containing protein.	0.543
ENSGGOP00000052295	GDI1	ENSGGOP00000052295	ENSGGOP00000013144	A20-type domain-containing protein.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.685
ENSGGOP00000052295	GDI2	ENSGGOP00000052295	ENSGGOP00000023008	A20-type domain-containing protein.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.685
ENSGGOP00000052295	RAB5A	ENSGGOP00000052295	ENSGGOP00000015584	A20-type domain-containing protein.	RAB5A, member RAS oncogene family.	0.974