STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRAG1PEAK1 related, kinase-activating pseudokinase 1. (1408 aa)    
Predicted Functional Partners:
ALDH2
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
      
 0.792
ENSGGOP00000031606
Stromal interaction molecule 1.
      
 0.761
GJA5
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.746
ITSN2
Intersectin 2.
     
 0.621
UBE2QL1
Ubiquitin conjugating enzyme E2 Q family like 1.
      
 0.564
PALB2
Partner and localizer of BRCA2.
      
 0.539
IFT140
Intraflagellar transport 140.
      
 0.522
MYOC
Myocilin.
      
 0.510
FAM20A
FAM20A golgi associated secretory pathway pseudokinase.
      
 0.509
ENSGGOP00000036466
Checkpoint kinase 2.
      
 0.496
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.