SPPL2C protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCTN1	MAPT	ENSGGOP00000040513	ENSGGOP00000005406	CAP-Gly domain-containing protein.	Microtubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabili [...]	0.811
DCTN1	PLCG1	ENSGGOP00000040513	ENSGGOP00000007654	CAP-Gly domain-containing protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.730
DCTN1	SPPL2C	ENSGGOP00000040513	ENSGGOP00000028132	CAP-Gly domain-containing protein.	Signal peptide peptidase like 2C.	0.464
DCTN1	SRRM2	ENSGGOP00000040513	ENSGGOP00000017023	CAP-Gly domain-containing protein.	Serine/arginine repetitive matrix 2.	0.770
G3QT76_GORGO	SPPL2C	ENSGGOP00000005887	ENSGGOP00000028132	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Signal peptide peptidase like 2C.	0.647
MAPT	DCTN1	ENSGGOP00000005406	ENSGGOP00000040513	Microtubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabili [...]	CAP-Gly domain-containing protein.	0.811
MAPT	SPPL2C	ENSGGOP00000005406	ENSGGOP00000028132	Microtubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabili [...]	Signal peptide peptidase like 2C.	0.449
MAPT	SRRM2	ENSGGOP00000005406	ENSGGOP00000017023	Microtubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabili [...]	Serine/arginine repetitive matrix 2.	0.547
ODF1	SHISA6	ENSGGOP00000024334	ENSGGOP00000021764	Outer dense fiber of sperm tails 1.	Shisa family member 6.	0.529
ODF1	SPATA18	ENSGGOP00000024334	ENSGGOP00000008306	Outer dense fiber of sperm tails 1.	Spermatogenesis associated 18.	0.500
ODF1	SPPL2C	ENSGGOP00000024334	ENSGGOP00000028132	Outer dense fiber of sperm tails 1.	Signal peptide peptidase like 2C.	0.483
PLCG1	DCTN1	ENSGGOP00000007654	ENSGGOP00000040513	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	CAP-Gly domain-containing protein.	0.730
PLCG1	SPPL2C	ENSGGOP00000007654	ENSGGOP00000028132	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Signal peptide peptidase like 2C.	0.643
PLCG1	SRRM2	ENSGGOP00000007654	ENSGGOP00000017023	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Serine/arginine repetitive matrix 2.	0.653
RCE1	SPPL2C	ENSGGOP00000014112	ENSGGOP00000028132	Ras converting CAAX endopeptidase 1.	Signal peptide peptidase like 2C.	0.473
SHISA6	ODF1	ENSGGOP00000021764	ENSGGOP00000024334	Shisa family member 6.	Outer dense fiber of sperm tails 1.	0.529
SHISA6	SPATA18	ENSGGOP00000021764	ENSGGOP00000008306	Shisa family member 6.	Spermatogenesis associated 18.	0.604
SHISA6	SPPL2C	ENSGGOP00000021764	ENSGGOP00000028132	Shisa family member 6.	Signal peptide peptidase like 2C.	0.486
SPATA18	ODF1	ENSGGOP00000008306	ENSGGOP00000024334	Spermatogenesis associated 18.	Outer dense fiber of sperm tails 1.	0.500
SPATA18	SHISA6	ENSGGOP00000008306	ENSGGOP00000021764	Spermatogenesis associated 18.	Shisa family member 6.	0.604