| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATG7 | UBA1 | ENSGGOP00000003435 | ENSGGOP00000007393 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | 0.626 |
| ATG7 | UBA3 | ENSGGOP00000003435 | ENSGGOP00000003886 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | Ubiquitin like modifier activating enzyme 3. | 0.777 |
| ATG7 | UBA5 | ENSGGOP00000003435 | ENSGGOP00000005966 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | Ubiquitin like modifier activating enzyme 5. | 0.737 |
| ATG7 | UBA52 | ENSGGOP00000003435 | ENSGGOP00000004534 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | Ubiquitin-like domain-containing protein. | 0.733 |
| ATG7 | UBA6 | ENSGGOP00000003435 | ENSGGOP00000014395 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | Ubiquitin like modifier activating enzyme 6. | 0.637 |
| ATG7 | UBE2G2 | ENSGGOP00000003435 | ENSGGOP00000040729 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. | 0.729 |
| ATG7 | UBE2H | ENSGGOP00000003435 | ENSGGOP00000034484 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. | 0.751 |
| ATG7 | UBE2J2 | ENSGGOP00000003435 | ENSGGOP00000005227 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | Ubiquitin conjugating enzyme E2 J2. | 0.751 |
| MARCHF6 | UBE2G2 | ENSGGOP00000004833 | ENSGGOP00000040729 | Membrane associated ring-CH-type finger 6. | Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. | 0.935 |
| MARCHF6 | UBE2J2 | ENSGGOP00000004833 | ENSGGOP00000005227 | Membrane associated ring-CH-type finger 6. | Ubiquitin conjugating enzyme E2 J2. | 0.835 |
| TMEM129 | UBE2J2 | ENSGGOP00000040429 | ENSGGOP00000005227 | Transmembrane protein 129. | Ubiquitin conjugating enzyme E2 J2. | 0.840 |
| UBA1 | ATG7 | ENSGGOP00000007393 | ENSGGOP00000003435 | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | 0.626 |
| UBA1 | UBA3 | ENSGGOP00000007393 | ENSGGOP00000003886 | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | Ubiquitin like modifier activating enzyme 3. | 0.649 |
| UBA1 | UBA5 | ENSGGOP00000007393 | ENSGGOP00000005966 | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | Ubiquitin like modifier activating enzyme 5. | 0.635 |
| UBA1 | UBA52 | ENSGGOP00000007393 | ENSGGOP00000004534 | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | Ubiquitin-like domain-containing protein. | 0.981 |
| UBA1 | UBA6 | ENSGGOP00000007393 | ENSGGOP00000014395 | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | Ubiquitin like modifier activating enzyme 6. | 0.978 |
| UBA1 | UBE2G2 | ENSGGOP00000007393 | ENSGGOP00000040729 | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. | 0.964 |
| UBA1 | UBE2H | ENSGGOP00000007393 | ENSGGOP00000034484 | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. | 0.960 |
| UBA1 | UBE2J2 | ENSGGOP00000007393 | ENSGGOP00000005227 | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | Ubiquitin conjugating enzyme E2 J2. | 0.809 |
| UBA3 | ATG7 | ENSGGOP00000003886 | ENSGGOP00000003435 | Ubiquitin like modifier activating enzyme 3. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | 0.777 |
