UBE2J2 protein (Gorilla gorilla) - STRING interaction network

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UBE2J2

Ubiquitin conjugating enzyme E2 J2. (275 aa)

Predicted Functional Partners:

TMEM129

0.934

ENSGGOP00000047423

0.893

DERL1

0.882

VCP

0.871

UBE2G2

0.858

SELENOS

0.855

ENSGGOP00000042981

0.757

MARCHF6

0.754

UBE2G1

0.729

ATG7

0.725

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG7	ENSGGOP00000042981	ENSGGOP00000003435	ENSGGOP00000042981	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.685
ATG7	ENSGGOP00000047423	ENSGGOP00000003435	ENSGGOP00000047423	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.902
ATG7	UBE2G1	ENSGGOP00000003435	ENSGGOP00000052129	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family.	0.669
ATG7	UBE2G2	ENSGGOP00000003435	ENSGGOP00000040729	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family.	0.720
ATG7	UBE2J2	ENSGGOP00000003435	ENSGGOP00000005227	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin conjugating enzyme E2 J2.	0.725
DERL1	MARCHF6	ENSGGOP00000008714	ENSGGOP00000004833	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Membrane associated ring-CH-type finger 6.	0.603
DERL1	SELENOS	ENSGGOP00000008714	ENSGGOP00000030198	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Uncharacterized protein.	0.990
DERL1	TMEM129	ENSGGOP00000008714	ENSGGOP00000040429	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Transmembrane protein 129.	0.931
DERL1	UBE2J2	ENSGGOP00000008714	ENSGGOP00000005227	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin conjugating enzyme E2 J2.	0.882
DERL1	VCP	ENSGGOP00000008714	ENSGGOP00000003146	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.997
ENSGGOP00000042981	ATG7	ENSGGOP00000042981	ENSGGOP00000003435	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.685
ENSGGOP00000042981	ENSGGOP00000047423	ENSGGOP00000042981	ENSGGOP00000047423	UBIQUITIN_CONJUGAT_2 domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.969
ENSGGOP00000042981	UBE2G1	ENSGGOP00000042981	ENSGGOP00000052129	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family.	0.603
ENSGGOP00000042981	UBE2G2	ENSGGOP00000042981	ENSGGOP00000040729	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family.	0.720
ENSGGOP00000042981	UBE2J2	ENSGGOP00000042981	ENSGGOP00000005227	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin conjugating enzyme E2 J2.	0.757
ENSGGOP00000047423	ATG7	ENSGGOP00000047423	ENSGGOP00000003435	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.902
ENSGGOP00000047423	ENSGGOP00000042981	ENSGGOP00000047423	ENSGGOP00000042981	UBIQUITIN_CONJUGAT_2 domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.969
ENSGGOP00000047423	UBE2G1	ENSGGOP00000047423	ENSGGOP00000052129	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family.	0.899
ENSGGOP00000047423	UBE2G2	ENSGGOP00000047423	ENSGGOP00000040729	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family.	0.927
ENSGGOP00000047423	UBE2J2	ENSGGOP00000047423	ENSGGOP00000005227	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin conjugating enzyme E2 J2.	0.893