node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APAF1 | BAK1 | ENSGGOP00000035421 | ENSGGOP00000018898 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | BCL2 antagonist/killer 1. | 0.633 |
APAF1 | BAX | ENSGGOP00000035421 | ENSGGOP00000010113 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | BCL2 associated X, apoptosis regulator. | 0.611 |
APAF1 | BCL2 | ENSGGOP00000035421 | ENSGGOP00000000778 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | BCL2 apoptosis regulator. | 0.913 |
APAF1 | BCL2L1 | ENSGGOP00000035421 | ENSGGOP00000020778 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | BCL2 like 1. | 0.895 |
APAF1 | CASP3 | ENSGGOP00000035421 | ENSGGOP00000021659 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 3; Belongs to the peptidase C14A family. | 0.995 |
APAF1 | CASP9 | ENSGGOP00000035421 | ENSGGOP00000001932 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 9; Belongs to the peptidase C14A family. | 0.999 |
APAF1 | CYCS | ENSGGOP00000035421 | ENSGGOP00000028382 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | 0.999 |
APAF1 | G3RZU2_GORGO | ENSGGOP00000035421 | ENSGGOP00000021335 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c1. | 0.528 |
APAF1 | HTRA2 | ENSGGOP00000035421 | ENSGGOP00000006190 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | HtrA serine peptidase 2. | 0.601 |
BAK1 | APAF1 | ENSGGOP00000018898 | ENSGGOP00000035421 | BCL2 antagonist/killer 1. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.633 |
BAK1 | BAX | ENSGGOP00000018898 | ENSGGOP00000010113 | BCL2 antagonist/killer 1. | BCL2 associated X, apoptosis regulator. | 0.955 |
BAK1 | BCL2 | ENSGGOP00000018898 | ENSGGOP00000000778 | BCL2 antagonist/killer 1. | BCL2 apoptosis regulator. | 0.988 |
BAK1 | BCL2L1 | ENSGGOP00000018898 | ENSGGOP00000020778 | BCL2 antagonist/killer 1. | BCL2 like 1. | 0.995 |
BAK1 | CASP3 | ENSGGOP00000018898 | ENSGGOP00000021659 | BCL2 antagonist/killer 1. | Caspase 3; Belongs to the peptidase C14A family. | 0.454 |
BAK1 | CASP9 | ENSGGOP00000018898 | ENSGGOP00000001932 | BCL2 antagonist/killer 1. | Caspase 9; Belongs to the peptidase C14A family. | 0.452 |
BAK1 | CYCS | ENSGGOP00000018898 | ENSGGOP00000028382 | BCL2 antagonist/killer 1. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | 0.968 |
BAX | APAF1 | ENSGGOP00000010113 | ENSGGOP00000035421 | BCL2 associated X, apoptosis regulator. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.611 |
BAX | BAK1 | ENSGGOP00000010113 | ENSGGOP00000018898 | BCL2 associated X, apoptosis regulator. | BCL2 antagonist/killer 1. | 0.955 |
BAX | BCL2 | ENSGGOP00000010113 | ENSGGOP00000000778 | BCL2 associated X, apoptosis regulator. | BCL2 apoptosis regulator. | 0.962 |
BAX | BCL2L1 | ENSGGOP00000010113 | ENSGGOP00000020778 | BCL2 associated X, apoptosis regulator. | BCL2 like 1. | 0.945 |