Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FCER1AFc fragment of IgE receptor Ia. (257 aa)    
Predicted Functional Partners:
MS4A2
Membrane spanning 4-domains A2.
   
 0.999
FCER1G
Uncharacterized protein.
   
 0.995
FYN
Tyrosine-protein kinase.
   
 0.949
SYK
Tyrosine-protein kinase.
    
 0.936
ENSGGOP00000047672
Ig-like domain-containing protein.
    
  0.913
ENSGGOP00000051390
Ig-like domain-containing protein.
    
  0.913
EPX
Eosinophil peroxidase.
   
  
 0.902
CPA3
Carboxypeptidase A3.
   
 
 0.835
LYN
Tyrosine-protein kinase.
   
 0.751
RNASE6
Ribonuclease K6; Ribonuclease which shows a preference for the pyrimidines uridine and cytosine. Has potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including P.aeruginosa, A.baumanii, M.luteus, S.aureus, E.faecalis, E.faecium, S.saprophyticus and E.coli. Causes loss of bacterial membrane integrity, and also promotes agglutination of Gram-negative bacteria. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity.
   
  
 0.680
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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