STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)    
Predicted Functional Partners:
NOTCH1
Uncharacterized protein.
   
0.999
NOTCH3
Notch receptor 3.
    
0.997
NOTCH4
Notch receptor 4.
   
0.992
NOTCH2
Notch receptor 2.
    
0.978
DLL1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
  
  
0.950
DLL3
Delta like canonical Notch ligand 3.
     
0.914
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.814
ENSGGOP00000049329
Uncharacterized protein.
    
 0.693
KDR
Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.671
HEY1
Hes related family bHLH transcription factor with YRPW motif 1.
    
 0.666
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: medium (60%) [HD]