STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AP1M1AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (435 aa)    
Predicted Functional Partners:
AP1G1
AP-1 complex subunit gamma.
   
 0.998
AP1B1
AP complex subunit beta.
   
 0.997
AP1S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.997
AP1S2-2
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.995
AP1S3
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.994
AP1G2
AP-1 complex subunit gamma.
   
 0.989
AP1S2
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.978
AP1M2
AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
  
 
0.955
GAK
Cyclin G associated kinase.
   
 0.927
ARF1
ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.
    
 0.911
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.