| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BAG6 | UBC | ENSGGOP00000040281 | ENSGGOP00000001286 | BCL2 associated athanogene 6. | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] | 0.492 |
| BAG6 | USP13 | ENSGGOP00000040281 | ENSGGOP00000028581 | BCL2 associated athanogene 6. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.813 |
| BECN1 | BECN2 | ENSGGOP00000001565 | ENSGGOP00000007989 | Beclin 1. | Beclin 2. | 0.905 |
| BECN1 | MCL1 | ENSGGOP00000001565 | ENSGGOP00000015756 | Beclin 1. | MCL1 apoptosis regulator, BCL2 family member. | 0.711 |
| BECN1 | USP13 | ENSGGOP00000001565 | ENSGGOP00000028581 | Beclin 1. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.861 |
| BECN2 | BECN1 | ENSGGOP00000007989 | ENSGGOP00000001565 | Beclin 2. | Beclin 1. | 0.905 |
| BECN2 | MCL1 | ENSGGOP00000007989 | ENSGGOP00000015756 | Beclin 2. | MCL1 apoptosis regulator, BCL2 family member. | 0.513 |
| BECN2 | USP13 | ENSGGOP00000007989 | ENSGGOP00000028581 | Beclin 2. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.848 |
| G3RNB7_GORGO | UBA52 | ENSGGOP00000017283 | ENSGGOP00000004534 | Uncharacterized protein. | Ubiquitin-like domain-containing protein. | 0.445 |
| G3RNB7_GORGO | UBC | ENSGGOP00000017283 | ENSGGOP00000001286 | Uncharacterized protein. | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] | 0.526 |
| G3RNB7_GORGO | USP13 | ENSGGOP00000017283 | ENSGGOP00000028581 | Uncharacterized protein. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.858 |
| MCL1 | BECN1 | ENSGGOP00000015756 | ENSGGOP00000001565 | MCL1 apoptosis regulator, BCL2 family member. | Beclin 1. | 0.711 |
| MCL1 | BECN2 | ENSGGOP00000015756 | ENSGGOP00000007989 | MCL1 apoptosis regulator, BCL2 family member. | Beclin 2. | 0.513 |
| MCL1 | USP13 | ENSGGOP00000015756 | ENSGGOP00000028581 | MCL1 apoptosis regulator, BCL2 family member. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.841 |
| PTEN | UBA52 | ENSGGOP00000000877 | ENSGGOP00000004534 | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | Ubiquitin-like domain-containing protein. | 0.445 |
| PTEN | UBC | ENSGGOP00000000877 | ENSGGOP00000001286 | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] | 0.526 |
| PTEN | USP13 | ENSGGOP00000000877 | ENSGGOP00000028581 | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.948 |
| SIAH1 | SIAH2 | ENSGGOP00000023833 | ENSGGOP00000014299 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | 0.927 |
| SIAH1 | UBA52 | ENSGGOP00000023833 | ENSGGOP00000004534 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | Ubiquitin-like domain-containing protein. | 0.944 |
| SIAH1 | UBC | ENSGGOP00000023833 | ENSGGOP00000001286 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] | 0.932 |
