| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BRCA1 | CDC6 | ENSGGOP00000023921 | ENSGGOP00000015116 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.411 |
| BRCA1 | CDK16 | ENSGGOP00000023921 | ENSGGOP00000028797 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Cyclin dependent kinase 16. | 0.692 |
| BRCA1 | CDK17 | ENSGGOP00000023921 | ENSGGOP00000001155 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Cyclin dependent kinase 17. | 0.528 |
| CCNG2 | CDC6 | ENSGGOP00000018335 | ENSGGOP00000015116 | Cyclin G2; Belongs to the cyclin family. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.605 |
| CCNG2 | CDK16 | ENSGGOP00000018335 | ENSGGOP00000028797 | Cyclin G2; Belongs to the cyclin family. | Cyclin dependent kinase 16. | 0.675 |
| CCNG2 | CDK17 | ENSGGOP00000018335 | ENSGGOP00000001155 | Cyclin G2; Belongs to the cyclin family. | Cyclin dependent kinase 17. | 0.752 |
| CCNY | CCNYL1 | ENSGGOP00000037945 | ENSGGOP00000030902 | Cyclin Y; Belongs to the cyclin family. | Cyclin Y like 1; Belongs to the cyclin family. | 0.868 |
| CCNY | CDK16 | ENSGGOP00000037945 | ENSGGOP00000028797 | Cyclin Y; Belongs to the cyclin family. | Cyclin dependent kinase 16. | 0.883 |
| CCNY | CDK17 | ENSGGOP00000037945 | ENSGGOP00000001155 | Cyclin Y; Belongs to the cyclin family. | Cyclin dependent kinase 17. | 0.635 |
| CCNY | ENSGGOP00000046041 | ENSGGOP00000037945 | ENSGGOP00000046041 | Cyclin Y; Belongs to the cyclin family. | Uncharacterized protein. | 0.811 |
| CCNY | YWHAH | ENSGGOP00000037945 | ENSGGOP00000005955 | Cyclin Y; Belongs to the cyclin family. | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. | 0.715 |
| CCNYL1 | CCNY | ENSGGOP00000030902 | ENSGGOP00000037945 | Cyclin Y like 1; Belongs to the cyclin family. | Cyclin Y; Belongs to the cyclin family. | 0.868 |
| CCNYL1 | CDK16 | ENSGGOP00000030902 | ENSGGOP00000028797 | Cyclin Y like 1; Belongs to the cyclin family. | Cyclin dependent kinase 16. | 0.848 |
| CCNYL1 | CDK17 | ENSGGOP00000030902 | ENSGGOP00000001155 | Cyclin Y like 1; Belongs to the cyclin family. | Cyclin dependent kinase 17. | 0.526 |
| CDC6 | BRCA1 | ENSGGOP00000015116 | ENSGGOP00000023921 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.411 |
| CDC6 | CCNG2 | ENSGGOP00000015116 | ENSGGOP00000018335 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Cyclin G2; Belongs to the cyclin family. | 0.605 |
| CDC6 | CDK16 | ENSGGOP00000015116 | ENSGGOP00000028797 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Cyclin dependent kinase 16. | 0.671 |
| CDC6 | CDK17 | ENSGGOP00000015116 | ENSGGOP00000001155 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Cyclin dependent kinase 17. | 0.671 |
| CDC6 | MCM3 | ENSGGOP00000015116 | ENSGGOP00000004909 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.997 |
| CDC6 | MCM4 | ENSGGOP00000015116 | ENSGGOP00000005952 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.988 |
