IPO5 protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASF1A	ASF1B	ENSGGOP00000009810	ENSGGOP00000012972	Anti-silencing function 1A histone chaperone.	Anti-silencing function 1B histone chaperone.	0.934
ASF1A	HAT1	ENSGGOP00000009810	ENSGGOP00000009140	Anti-silencing function 1A histone chaperone.	Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.	0.956
ASF1A	IPO5	ENSGGOP00000009810	ENSGGOP00000029121	Anti-silencing function 1A histone chaperone.	Importin 5.	0.687
ASF1B	ASF1A	ENSGGOP00000012972	ENSGGOP00000009810	Anti-silencing function 1B histone chaperone.	Anti-silencing function 1A histone chaperone.	0.934
ASF1B	HAT1	ENSGGOP00000012972	ENSGGOP00000009140	Anti-silencing function 1B histone chaperone.	Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.	0.950
ASF1B	IPO5	ENSGGOP00000012972	ENSGGOP00000029121	Anti-silencing function 1B histone chaperone.	Importin 5.	0.687
DDX56	IPO5	ENSGGOP00000011746	ENSGGOP00000029121	DEAD-box helicase 56.	Importin 5.	0.626
DDX56	NAT10	ENSGGOP00000011746	ENSGGOP00000034321	DEAD-box helicase 56.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.876
DDX56	POLR1A	ENSGGOP00000011746	ENSGGOP00000001765	DEAD-box helicase 56.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.713
DDX56	POLR1B	ENSGGOP00000011746	ENSGGOP00000013164	DEAD-box helicase 56.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.735
DDX56	RRP12	ENSGGOP00000011746	ENSGGOP00000014500	DEAD-box helicase 56.	Ribosomal RNA processing 12 homolog.	0.763
HAT1	ASF1A	ENSGGOP00000009140	ENSGGOP00000009810	Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.	Anti-silencing function 1A histone chaperone.	0.956
HAT1	ASF1B	ENSGGOP00000009140	ENSGGOP00000012972	Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.	Anti-silencing function 1B histone chaperone.	0.950
HAT1	IPO5	ENSGGOP00000009140	ENSGGOP00000029121	Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.	Importin 5.	0.645
IPO5	ASF1A	ENSGGOP00000029121	ENSGGOP00000009810	Importin 5.	Anti-silencing function 1A histone chaperone.	0.687
IPO5	ASF1B	ENSGGOP00000029121	ENSGGOP00000012972	Importin 5.	Anti-silencing function 1B histone chaperone.	0.687
IPO5	DDX56	ENSGGOP00000029121	ENSGGOP00000011746	Importin 5.	DEAD-box helicase 56.	0.626
IPO5	HAT1	ENSGGOP00000029121	ENSGGOP00000009140	Importin 5.	Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.	0.645
IPO5	KPNB1	ENSGGOP00000029121	ENSGGOP00000007915	Importin 5.	Karyopherin subunit beta 1.	0.763
IPO5	NAT10	ENSGGOP00000029121	ENSGGOP00000034321	Importin 5.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.670