STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIX3Homeobox domain-containing protein. (212 aa)    
Predicted Functional Partners:
RRS1
Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.
      
 0.845
MACC1
MET transcriptional regulator MACC1.
      
 0.834
DNMBP
Dynamin binding protein.
      
 0.800
ZIC2
Zic family member 2.
   
  
 0.762
PAX6
Uncharacterized protein.
   
 
 0.718
MDC1
Mediator of DNA damage checkpoint 1.
      
 0.711
CNTN2
Contactin 2.
      
 0.691
OTX2
Orthodenticle homeobox 2.
   
 
 0.689
DISP1
Dispatched RND transporter family member 1.
      
 0.673
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.672
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.