RAB4B protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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co-expression

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gene neighborhood

gene co-occurrence

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Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARF6	RAB4A	ENSGGOP00000041760	ENSGGOP00000015336	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	RAB4A, member RAS oncogene family.	0.551
ARF6	RAB4B	ENSGGOP00000041760	ENSGGOP00000031418	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.610
G3QLX7_GORGO	RAB4A	ENSGGOP00000003501	ENSGGOP00000015336	RUN domain-containing protein.	RAB4A, member RAS oncogene family.	0.978
G3QLX7_GORGO	RAB4B	ENSGGOP00000003501	ENSGGOP00000031418	RUN domain-containing protein.	Uncharacterized protein.	0.670
G3REU9_GORGO	RAB4A	ENSGGOP00000014096	ENSGGOP00000015336	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	RAB4A, member RAS oncogene family.	0.418
G3REU9_GORGO	RAB4B	ENSGGOP00000014096	ENSGGOP00000031418	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	Uncharacterized protein.	0.628
GDI1	RAB4A	ENSGGOP00000013144	ENSGGOP00000015336	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	RAB4A, member RAS oncogene family.	0.825
GDI1	RAB4B	ENSGGOP00000013144	ENSGGOP00000031418	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	Uncharacterized protein.	0.739
HGS	RAB4A	ENSGGOP00000009137	ENSGGOP00000015336	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	RAB4A, member RAS oncogene family.	0.786
HGS	RAB4B	ENSGGOP00000009137	ENSGGOP00000031418	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Uncharacterized protein.	0.641
HGS	RBSN	ENSGGOP00000009137	ENSGGOP00000012468	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Rabenosyn, RAB effector.	0.850
HGS	STAM	ENSGGOP00000009137	ENSGGOP00000000303	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Signal transducing adaptor molecule.	0.999
RAB4A	ARF6	ENSGGOP00000015336	ENSGGOP00000041760	RAB4A, member RAS oncogene family.	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	0.551
RAB4A	G3QLX7_GORGO	ENSGGOP00000015336	ENSGGOP00000003501	RAB4A, member RAS oncogene family.	RUN domain-containing protein.	0.978
RAB4A	G3REU9_GORGO	ENSGGOP00000015336	ENSGGOP00000014096	RAB4A, member RAS oncogene family.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.418
RAB4A	GDI1	ENSGGOP00000015336	ENSGGOP00000013144	RAB4A, member RAS oncogene family.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.825
RAB4A	HGS	ENSGGOP00000015336	ENSGGOP00000009137	RAB4A, member RAS oncogene family.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.786
RAB4A	RAB4B	ENSGGOP00000015336	ENSGGOP00000031418	RAB4A, member RAS oncogene family.	Uncharacterized protein.	0.945
RAB4A	RABEP1	ENSGGOP00000015336	ENSGGOP00000044014	RAB4A, member RAS oncogene family.	Rabaptin, RAB GTPase binding effector protein 1.	0.860
RAB4A	RBSN	ENSGGOP00000015336	ENSGGOP00000012468	RAB4A, member RAS oncogene family.	Rabenosyn, RAB effector.	0.994