Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LCKTyrosine-protein kinase. (524 aa)    
Predicted Functional Partners:
G3QGN8_GORGO
Tyrosine-protein kinase.
  
0.999
G3RV54_GORGO
Protein tyrosine phosphatase receptor type C.
   
 0.996
FYN
Tyrosine-protein kinase.
  
0.992
CD8A
CD8a molecule.
   
 0.990
CD4
CD4 molecule.
   
 0.988
CD247
CD247 molecule.
   
 0.977
G3RS61_GORGO
Cbl proto-oncogene B.
    
 0.971
CBL
Cbl proto-oncogene.
    
 0.962
TYROBP
TYRO protein tyrosine kinase binding protein.
   
 0.945
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.935
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.