NPC2 protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NPC2

ML domain-containing protein. (221 aa)

Predicted Functional Partners:

NPC1

0.999

NPC1L1

0.940

SCAP

0.836

ENSGGOP00000045173

0.836

ENSGGOP00000043184

0.674

STARD3NL

0.672

NUDT19

0.670

APOB

0.646

GM2A

0.632

G3QM33_GORGO

0.592

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOB	NPC1L1	ENSGGOP00000020316	ENSGGOP00000022024	Apolipoprotein B.	NPC1 like intracellular cholesterol transporter 1.	0.673
APOB	NPC2	ENSGGOP00000020316	ENSGGOP00000039960	Apolipoprotein B.	ML domain-containing protein.	0.646
ENSGGOP00000043184	NPC1	ENSGGOP00000043184	ENSGGOP00000005017	Uncharacterized protein.	NPC intracellular cholesterol transporter 1.	0.672
ENSGGOP00000043184	NPC2	ENSGGOP00000043184	ENSGGOP00000039960	Uncharacterized protein.	ML domain-containing protein.	0.674
ENSGGOP00000043184	STARD3NL	ENSGGOP00000043184	ENSGGOP00000013138	Uncharacterized protein.	STARD3 N-terminal like.	0.917
ENSGGOP00000045173	NPC2	ENSGGOP00000045173	ENSGGOP00000039960	Uncharacterized protein.	ML domain-containing protein.	0.836
ENSGGOP00000045173	SCAP	ENSGGOP00000045173	ENSGGOP00000037185	Uncharacterized protein.	SSD domain-containing protein.	0.951
G3QM33_GORGO	NPC2	ENSGGOP00000003559	ENSGGOP00000039960	Uncharacterized protein.	ML domain-containing protein.	0.592
GM2A	NPC2	ENSGGOP00000014927	ENSGGOP00000039960	GM2 ganglioside activator.	ML domain-containing protein.	0.632
NPC1	ENSGGOP00000043184	ENSGGOP00000005017	ENSGGOP00000043184	NPC intracellular cholesterol transporter 1.	Uncharacterized protein.	0.672
NPC1	NPC2	ENSGGOP00000005017	ENSGGOP00000039960	NPC intracellular cholesterol transporter 1.	ML domain-containing protein.	0.999
NPC1	STARD3NL	ENSGGOP00000005017	ENSGGOP00000013138	NPC intracellular cholesterol transporter 1.	STARD3 N-terminal like.	0.569
NPC1L1	APOB	ENSGGOP00000022024	ENSGGOP00000020316	NPC1 like intracellular cholesterol transporter 1.	Apolipoprotein B.	0.673
NPC1L1	NPC2	ENSGGOP00000022024	ENSGGOP00000039960	NPC1 like intracellular cholesterol transporter 1.	ML domain-containing protein.	0.940
NPC2	APOB	ENSGGOP00000039960	ENSGGOP00000020316	ML domain-containing protein.	Apolipoprotein B.	0.646
NPC2	ENSGGOP00000043184	ENSGGOP00000039960	ENSGGOP00000043184	ML domain-containing protein.	Uncharacterized protein.	0.674
NPC2	ENSGGOP00000045173	ENSGGOP00000039960	ENSGGOP00000045173	ML domain-containing protein.	Uncharacterized protein.	0.836
NPC2	G3QM33_GORGO	ENSGGOP00000039960	ENSGGOP00000003559	ML domain-containing protein.	Uncharacterized protein.	0.592
NPC2	GM2A	ENSGGOP00000039960	ENSGGOP00000014927	ML domain-containing protein.	GM2 ganglioside activator.	0.632
NPC2	NPC1	ENSGGOP00000039960	ENSGGOP00000005017	ML domain-containing protein.	NPC intracellular cholesterol transporter 1.	0.999