Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TIMP1TIMP metallopeptidase inhibitor 1. (207 aa)    
Predicted Functional Partners:
MMP9
Matrix metallopeptidase 9.
   
 0.992
MMP14
Matrix metallopeptidase 14.
   
 0.943
MMP1
Matrix metallopeptidase 1.
   
 0.929
MMP3
Matrix metallopeptidase 3.
   
 0.929
CD63
Tetraspanin.
   
 0.915
ELSPBP1
Epididymal sperm binding protein 1.
   
 0.911
MMP10
Matrix metallopeptidase 10.
   
 0.899
MMP2
Matrix metallopeptidase 2.
   
 0.828
MMP15
Matrix metallopeptidase 15.
   
 0.816
MMP8
Matrix metallopeptidase 8.
   
 0.803
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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