ENSGGOP00000043083 protein (Gorilla gorilla)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Knowledge-based Evidence

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experimentally determined

co-expression

Genomic Predictions

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gene co-occurrence

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Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	ENSGGOP00000038823	ENSGGOP00000033876	ENSGGOP00000038823	Androgen receptor.	Nuclear receptor corepressor 1.	0.961
AR	ENSGGOP00000043083	ENSGGOP00000033876	ENSGGOP00000043083	Androgen receptor.	Nuclear receptor corepressor 2.	0.959
AR	HDAC1	ENSGGOP00000033876	ENSGGOP00000011454	Androgen receptor.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.886
AR	HDAC2	ENSGGOP00000033876	ENSGGOP00000005320	Androgen receptor.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.738
AR	HDAC3	ENSGGOP00000033876	ENSGGOP00000015976	Androgen receptor.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.542
ENSGGOP00000038823	AR	ENSGGOP00000038823	ENSGGOP00000033876	Nuclear receptor corepressor 1.	Androgen receptor.	0.961
ENSGGOP00000038823	ENSGGOP00000043083	ENSGGOP00000038823	ENSGGOP00000043083	Nuclear receptor corepressor 1.	Nuclear receptor corepressor 2.	0.977
ENSGGOP00000038823	HDAC1	ENSGGOP00000038823	ENSGGOP00000011454	Nuclear receptor corepressor 1.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.977
ENSGGOP00000038823	HDAC2	ENSGGOP00000038823	ENSGGOP00000005320	Nuclear receptor corepressor 1.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.947
ENSGGOP00000038823	HDAC3	ENSGGOP00000038823	ENSGGOP00000015976	Nuclear receptor corepressor 1.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.999
ENSGGOP00000038823	PPARG	ENSGGOP00000038823	ENSGGOP00000032598	Nuclear receptor corepressor 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.974
ENSGGOP00000038823	RARA	ENSGGOP00000038823	ENSGGOP00000003063	Nuclear receptor corepressor 1.	Uncharacterized protein.	0.967
ENSGGOP00000038823	RBPJ	ENSGGOP00000038823	ENSGGOP00000042772	Nuclear receptor corepressor 1.	Recombination signal binding protein for immunoglobulin kappa J region.	0.756
ENSGGOP00000038823	RBPJL	ENSGGOP00000038823	ENSGGOP00000004070	Nuclear receptor corepressor 1.	Recombination signal binding protein for immunoglobulin kappa J region like.	0.666
ENSGGOP00000038823	SIN3A	ENSGGOP00000038823	ENSGGOP00000035548	Nuclear receptor corepressor 1.	Uncharacterized protein.	0.991
ENSGGOP00000043083	AR	ENSGGOP00000043083	ENSGGOP00000033876	Nuclear receptor corepressor 2.	Androgen receptor.	0.959
ENSGGOP00000043083	ENSGGOP00000038823	ENSGGOP00000043083	ENSGGOP00000038823	Nuclear receptor corepressor 2.	Nuclear receptor corepressor 1.	0.977
ENSGGOP00000043083	HDAC1	ENSGGOP00000043083	ENSGGOP00000011454	Nuclear receptor corepressor 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.983
ENSGGOP00000043083	HDAC2	ENSGGOP00000043083	ENSGGOP00000005320	Nuclear receptor corepressor 2.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.972
ENSGGOP00000043083	HDAC3	ENSGGOP00000043083	ENSGGOP00000015976	Nuclear receptor corepressor 2.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.992