STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRSS8Serine protease 8; Belongs to the peptidase S1 family. (349 aa)    
Predicted Functional Partners:
SPINT1
Serine peptidase inhibitor, Kunitz type 1.
   
 0.769
SPINT2
Serine peptidase inhibitor, Kunitz type 2.
   
 0.706
IRF6
Interferon regulatory factor 6.
   
 
 0.539
TMEM63A
Transmembrane protein 63A.
   
  
 0.537
SCNN1A
Sodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
   
  
 0.530
ZNF157
Zinc finger protein 157.
    
 
 0.530
DSP
Desmoplakin.
      
 0.510
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
  
 
 0.501
PTGER3
Prostaglandin E receptor 3.
   
 0.493
TJP3
Tight junction protein 3; Belongs to the MAGUK family.
   
  
 0.486
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.