| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CASP10 | CFLAR | ENSGGOP00000011996 | ENSGGOP00000010692 | Caspase 10; Belongs to the peptidase C14A family. | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | 0.998 |
| CASP10 | ENSGGOP00000033404 | ENSGGOP00000011996 | ENSGGOP00000033404 | Caspase 10; Belongs to the peptidase C14A family. | Caspase 8; Belongs to the peptidase C14A family. | 0.997 |
| CASP10 | FADD | ENSGGOP00000011996 | ENSGGOP00000020107 | Caspase 10; Belongs to the peptidase C14A family. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.999 |
| CASP10 | FAS | ENSGGOP00000011996 | ENSGGOP00000027099 | Caspase 10; Belongs to the peptidase C14A family. | Fas cell surface death receptor. | 0.977 |
| CASP10 | G3QYB0_GORGO | ENSGGOP00000011996 | ENSGGOP00000007840 | Caspase 10; Belongs to the peptidase C14A family. | TNF receptor superfamily member 10d. | 0.567 |
| CASP10 | G3RF33_GORGO | ENSGGOP00000011996 | ENSGGOP00000047069 | Caspase 10; Belongs to the peptidase C14A family. | Tumor necrosis factor ligand superfamily member. | 0.875 |
| CASP10 | RIPK1 | ENSGGOP00000011996 | ENSGGOP00000012277 | Caspase 10; Belongs to the peptidase C14A family. | Receptor interacting serine/threonine kinase 1. | 0.973 |
| CASP10 | TNFRSF10A | ENSGGOP00000011996 | ENSGGOP00000046895 | Caspase 10; Belongs to the peptidase C14A family. | TNF receptor superfamily member 10a. | 0.806 |
| CASP10 | TNFRSF10B | ENSGGOP00000011996 | ENSGGOP00000010773 | Caspase 10; Belongs to the peptidase C14A family. | TNF receptor superfamily member 10b. | 0.866 |
| CFLAR | CASP10 | ENSGGOP00000010692 | ENSGGOP00000011996 | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | Caspase 10; Belongs to the peptidase C14A family. | 0.998 |
| CFLAR | ENSGGOP00000033404 | ENSGGOP00000010692 | ENSGGOP00000033404 | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | Caspase 8; Belongs to the peptidase C14A family. | 0.991 |
| CFLAR | FADD | ENSGGOP00000010692 | ENSGGOP00000020107 | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.998 |
| CFLAR | FAS | ENSGGOP00000010692 | ENSGGOP00000027099 | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | Fas cell surface death receptor. | 0.963 |
| CFLAR | G3QYB0_GORGO | ENSGGOP00000010692 | ENSGGOP00000007840 | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | TNF receptor superfamily member 10d. | 0.548 |
| CFLAR | G3RF33_GORGO | ENSGGOP00000010692 | ENSGGOP00000047069 | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | Tumor necrosis factor ligand superfamily member. | 0.966 |
| CFLAR | RIPK1 | ENSGGOP00000010692 | ENSGGOP00000012277 | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | Receptor interacting serine/threonine kinase 1. | 0.952 |
| CFLAR | TNFRSF10A | ENSGGOP00000010692 | ENSGGOP00000046895 | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | TNF receptor superfamily member 10a. | 0.974 |
| CFLAR | TNFRSF10B | ENSGGOP00000010692 | ENSGGOP00000010773 | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | TNF receptor superfamily member 10b. | 0.951 |
| CFLAR | TNFRSF10C | ENSGGOP00000010692 | ENSGGOP00000050601 | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. | TNF receptor superfamily member 10c. | 0.470 |
| ENSGGOP00000033404 | CASP10 | ENSGGOP00000033404 | ENSGGOP00000011996 | Caspase 8; Belongs to the peptidase C14A family. | Caspase 10; Belongs to the peptidase C14A family. | 0.997 |
