OXSM protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBR4	FASN	ENSGGOP00000023511	ENSGGOP00000011384	Carbonyl reductase 4.	Fatty acid synthase.	0.928
CBR4	G3QCT3_GORGO	ENSGGOP00000023511	ENSGGOP00000000029	Carbonyl reductase 4.	Malonyl-CoA-acyl carrier protein transacylase.	0.531
CBR4	HSD17B8	ENSGGOP00000023511	ENSGGOP00000009610	Carbonyl reductase 4.	Hydroxysteroid 17-beta dehydrogenase 8.	0.999
CBR4	MECR	ENSGGOP00000023511	ENSGGOP00000003071	Carbonyl reductase 4.	PKS_ER domain-containing protein.	0.556
CBR4	NDUFAB1	ENSGGOP00000023511	ENSGGOP00000006175	Carbonyl reductase 4.	Acyl carrier protein, mitochondrial; Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity). Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity).	0.413
CBR4	OXSM	ENSGGOP00000023511	ENSGGOP00000048189	Carbonyl reductase 4.	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.968
CBR4	PALB2	ENSGGOP00000023511	ENSGGOP00000012506	Carbonyl reductase 4.	Partner and localizer of BRCA2.	0.413
ELOVL6	FASN	ENSGGOP00000000217	ENSGGOP00000011384	Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...]	Fatty acid synthase.	0.809
ELOVL6	OXSM	ENSGGOP00000000217	ENSGGOP00000048189	Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...]	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.930
ENSGGOP00000035240	NDUFAB1	ENSGGOP00000035240	ENSGGOP00000006175	Uncharacterized protein; Belongs to the complex I LYR family.	Acyl carrier protein, mitochondrial; Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity). Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity).	0.923
ENSGGOP00000035240	OXSM	ENSGGOP00000035240	ENSGGOP00000048189	Uncharacterized protein; Belongs to the complex I LYR family.	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.847
ENSGGOP00000035240	PALB2	ENSGGOP00000035240	ENSGGOP00000012506	Uncharacterized protein; Belongs to the complex I LYR family.	Partner and localizer of BRCA2.	0.655
FASN	CBR4	ENSGGOP00000011384	ENSGGOP00000023511	Fatty acid synthase.	Carbonyl reductase 4.	0.928
FASN	ELOVL6	ENSGGOP00000011384	ENSGGOP00000000217	Fatty acid synthase.	Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...]	0.809
FASN	G3QCT3_GORGO	ENSGGOP00000011384	ENSGGOP00000000029	Fatty acid synthase.	Malonyl-CoA-acyl carrier protein transacylase.	0.960
FASN	HSD17B8	ENSGGOP00000011384	ENSGGOP00000009610	Fatty acid synthase.	Hydroxysteroid 17-beta dehydrogenase 8.	0.929
FASN	LIPT1	ENSGGOP00000011384	ENSGGOP00000021620	Fatty acid synthase.	Lipoyltransferase 1.	0.818
FASN	MECR	ENSGGOP00000011384	ENSGGOP00000003071	Fatty acid synthase.	PKS_ER domain-containing protein.	0.949
FASN	NDUFAB1	ENSGGOP00000011384	ENSGGOP00000006175	Fatty acid synthase.	Acyl carrier protein, mitochondrial; Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity). Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity).	0.722
FASN	OXSM	ENSGGOP00000011384	ENSGGOP00000048189	Fatty acid synthase.	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.937