close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDKN1BUncharacterized protein. (205 aa)    
Predicted Functional Partners:
CDK4
Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.999
CCNA2
Cyclin A2; Belongs to the cyclin family.
    
 0.999
CCNE1
Cyclin E1; Belongs to the cyclin family.
   
 0.999
CCND2
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.999
CCND3
Cyclin D3; Belongs to the cyclin family.
   
 0.999
SKP2
S-phase kinase associated protein 2.
    
 0.999
CCNA1
Cyclin A1; Belongs to the cyclin family.
    
 0.999
ENSGGOP00000050973
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.999
G3SAP1_GORGO
Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.997
CCND1
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.997
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.