HDAC6 protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTTN	HDAC6	ENSGGOP00000002964	ENSGGOP00000049791	Cortactin.	Histone deacetylase 6.	0.902
EP300	G3S4Z2_GORGO	ENSGGOP00000008032	ENSGGOP00000023146	E1A binding protein p300.	Uncharacterized protein.	0.470
EP300	HDAC6	ENSGGOP00000008032	ENSGGOP00000049791	E1A binding protein p300.	Histone deacetylase 6.	0.906
EP300	HSP90AB1	ENSGGOP00000008032	ENSGGOP00000008695	E1A binding protein p300.	Heat shock protein 90 alpha family class B member 1.	0.426
EP300	SIRT2	ENSGGOP00000008032	ENSGGOP00000002451	E1A binding protein p300.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.851
G3RQF7_GORGO	G3S4Z2_GORGO	ENSGGOP00000018030	ENSGGOP00000023146	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.631
G3RQF7_GORGO	HDAC6	ENSGGOP00000018030	ENSGGOP00000049791	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Histone deacetylase 6.	0.932
G3RQF7_GORGO	VCP	ENSGGOP00000018030	ENSGGOP00000003146	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Valosin containing protein; Belongs to the AAA ATPase family.	0.514
G3S4Z2_GORGO	EP300	ENSGGOP00000023146	ENSGGOP00000008032	Uncharacterized protein.	E1A binding protein p300.	0.470
G3S4Z2_GORGO	G3RQF7_GORGO	ENSGGOP00000023146	ENSGGOP00000018030	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.631
G3S4Z2_GORGO	HDAC6	ENSGGOP00000023146	ENSGGOP00000049791	Uncharacterized protein.	Histone deacetylase 6.	0.969
G3S4Z2_GORGO	HSP90AB1	ENSGGOP00000023146	ENSGGOP00000008695	Uncharacterized protein.	Heat shock protein 90 alpha family class B member 1.	0.999
G3S4Z2_GORGO	PRKN	ENSGGOP00000023146	ENSGGOP00000038323	Uncharacterized protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.859
G3S4Z2_GORGO	TARDBP	ENSGGOP00000023146	ENSGGOP00000014979	Uncharacterized protein.	RRM domain-containing protein.	0.419
G3S4Z2_GORGO	VCP	ENSGGOP00000023146	ENSGGOP00000003146	Uncharacterized protein.	Valosin containing protein; Belongs to the AAA ATPase family.	0.874
HDAC6	CTTN	ENSGGOP00000049791	ENSGGOP00000002964	Histone deacetylase 6.	Cortactin.	0.902
HDAC6	EP300	ENSGGOP00000049791	ENSGGOP00000008032	Histone deacetylase 6.	E1A binding protein p300.	0.906
HDAC6	G3RQF7_GORGO	ENSGGOP00000049791	ENSGGOP00000018030	Histone deacetylase 6.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.932
HDAC6	G3S4Z2_GORGO	ENSGGOP00000049791	ENSGGOP00000023146	Histone deacetylase 6.	Uncharacterized protein.	0.969
HDAC6	HSP90AB1	ENSGGOP00000049791	ENSGGOP00000008695	Histone deacetylase 6.	Heat shock protein 90 alpha family class B member 1.	0.869